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Anti-VTI1A monoclonal antibody
Pre-made anti-VTI1A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to VTI1A/VTI1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2269-Ab-1/ GM-Tg-hg-IP2269-Ab-2 | Anti-Human VTI1A monoclonal antibody | Human |
| GM-Tg-rg-IP2269-Ab-1/ GM-Tg-rg-IP2269-Ab-2 | Anti-Rat VTI1A monoclonal antibody | Rat |
| GM-Tg-mg-IP2269-Ab-1/ GM-Tg-mg-IP2269-Ab-2 | Anti-Mouse VTI1A monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2269-Ab-1/ GM-Tg-cynog-IP2269-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VTI1A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2269-Ab-1/ GM-Tg-felg-IP2269-Ab-2 | Anti-Feline VTI1A monoclonal antibody | Feline |
| GM-Tg-cang-IP2269-Ab-1/ GM-Tg-cang-IP2269-Ab-2 | Anti-Canine VTI1A monoclonal antibody | Canine |
| GM-Tg-bovg-IP2269-Ab-1/ GM-Tg-bovg-IP2269-Ab-2 | Anti-Bovine VTI1A monoclonal antibody | Bovine |
| GM-Tg-equg-IP2269-Ab-1/ GM-Tg-equg-IP2269-Ab-2 | Anti-Equine VTI1A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2269-Ab-1/ GM-Tg-hg-IP2269-Ab-2; GM-Tg-rg-IP2269-Ab-1/ GM-Tg-rg-IP2269-Ab-2; GM-Tg-mg-IP2269-Ab-1/ GM-Tg-mg-IP2269-Ab-2; GM-Tg-cynog-IP2269-Ab-1/ GM-Tg-cynog-IP2269-Ab-2; GM-Tg-felg-IP2269-Ab-1/ GM-Tg-felg-IP2269-Ab-2; GM-Tg-cang-IP2269-Ab-1/ GM-Tg-cang-IP2269-Ab-2; GM-Tg-bovg-IP2269-Ab-1/ GM-Tg-bovg-IP2269-Ab-2; GM-Tg-equg-IP2269-Ab-1/ GM-Tg-equg-IP2269-Ab-2 |
| Products Name | Anti-VTI1A monoclonal antibody |
| Format | mab |
| Target Name | VTI1A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-VTI1A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2269-Ag-1 | Recombinant multi-species VTI1A/ MMDS3/ MVti1 protein |
Target information
| Target ID | GM-IP2269 |
| Target Name | VTI1A |
| Gene ID | 143187,53611,65277,696654,100685447,101095380,780850,100068586 |
| Gene Symbol and Synonyms | 1110014F16Rik,1110018K19Rik,4921537J05Rik,DD6A4-2(1),MMDS3,MVti1,MVti1a,Vti1,Vti1-rp2,VTI1A,VTI1RP2 |
| Uniprot Accession | Q96AJ9,Q9JI51 |
| Uniprot Entry Name | VTI1A_HUMAN,VTI1A_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000151532 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: VTI1A, gene name: VTI1A, also named as MMDS3, MVti1, VTI1RP2, Vti1-rp2. The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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