Anti-ZDHHC8 monoclonal antibody

Pre-made anti-ZDHHC8 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ZDHHC8/ZDHHC8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2312-Ab-1/ GM-Tg-hg-IP2312-Ab-2Anti-Human ZDHHC8 monoclonal antibodyHuman
GM-Tg-rg-IP2312-Ab-1/ GM-Tg-rg-IP2312-Ab-2Anti-Rat ZDHHC8 monoclonal antibodyRat
GM-Tg-mg-IP2312-Ab-1/ GM-Tg-mg-IP2312-Ab-2Anti-Mouse ZDHHC8 monoclonal antibodyMouse
GM-Tg-cynog-IP2312-Ab-1/ GM-Tg-cynog-IP2312-Ab-2Anti-Cynomolgus/ Rhesus macaque ZDHHC8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2312-Ab-1/ GM-Tg-felg-IP2312-Ab-2Anti-Feline ZDHHC8 monoclonal antibodyFeline
GM-Tg-cang-IP2312-Ab-1/ GM-Tg-cang-IP2312-Ab-2Anti-Canine ZDHHC8 monoclonal antibodyCanine
GM-Tg-bovg-IP2312-Ab-1/ GM-Tg-bovg-IP2312-Ab-2Anti-Bovine ZDHHC8 monoclonal antibodyBovine
GM-Tg-equg-IP2312-Ab-1/ GM-Tg-equg-IP2312-Ab-2Anti-Equine ZDHHC8 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2312-Ab-1/ GM-Tg-hg-IP2312-Ab-2; GM-Tg-rg-IP2312-Ab-1/ GM-Tg-rg-IP2312-Ab-2;
GM-Tg-mg-IP2312-Ab-1/ GM-Tg-mg-IP2312-Ab-2; GM-Tg-cynog-IP2312-Ab-1/ GM-Tg-cynog-IP2312-Ab-2;
GM-Tg-felg-IP2312-Ab-1/ GM-Tg-felg-IP2312-Ab-2; GM-Tg-cang-IP2312-Ab-1/ GM-Tg-cang-IP2312-Ab-2;
GM-Tg-bovg-IP2312-Ab-1/ GM-Tg-bovg-IP2312-Ab-2; GM-Tg-equg-IP2312-Ab-1/ GM-Tg-equg-IP2312-Ab-2
Products NameAnti-ZDHHC8 monoclonal antibody
Formatmab
Target NameZDHHC8
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-ZDHHC8 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2312-Ag-1Recombinant multi-species ZDHC8/ ZDHHC8/ DHHC8 protein


    Target information

    Target IDGM-IP2312
    Target NameZDHHC8
    Gene ID29801,27801,303796,712832,486415,101095862,526847,100051594
    Gene Symbol and SynonymsD16H22S1738E,DHHC-8,DHHC8,E330009O14Rik,Op53c05,ZDHHC8,ZDHHCL1,ZNF378
    Uniprot AccessionQ9ULC8,Q2THW8
    Uniprot Entry NameZDHC8_HUMAN,ZDHC8_CANLF
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000099904
    Target ClassificationN/A

    The target: ZDHHC8, gene name: ZDHHC8, also named as DHHC8, ZDHHCL1, ZNF378. This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.