Anti-ZNRF4 monoclonal antibody

Pre-made anti-ZNRF4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ZNRF4/ZNRF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2326-Ab-1/ GM-Tg-hg-IP2326-Ab-2Anti-Human ZNRF4 monoclonal antibodyHuman
GM-Tg-rg-IP2326-Ab-1/ GM-Tg-rg-IP2326-Ab-2Anti-Rat ZNRF4 monoclonal antibodyRat
GM-Tg-mg-IP2326-Ab-1/ GM-Tg-mg-IP2326-Ab-2Anti-Mouse ZNRF4 monoclonal antibodyMouse
GM-Tg-cynog-IP2326-Ab-1/ GM-Tg-cynog-IP2326-Ab-2Anti-Cynomolgus/ Rhesus macaque ZNRF4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2326-Ab-1/ GM-Tg-felg-IP2326-Ab-2Anti-Feline ZNRF4 monoclonal antibodyFeline
GM-Tg-cang-IP2326-Ab-1/ GM-Tg-cang-IP2326-Ab-2Anti-Canine ZNRF4 monoclonal antibodyCanine
GM-Tg-bovg-IP2326-Ab-1/ GM-Tg-bovg-IP2326-Ab-2Anti-Bovine ZNRF4 monoclonal antibodyBovine
GM-Tg-equg-IP2326-Ab-1/ GM-Tg-equg-IP2326-Ab-2Anti-Equine ZNRF4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2326-Ab-1/ GM-Tg-hg-IP2326-Ab-2; GM-Tg-rg-IP2326-Ab-1/ GM-Tg-rg-IP2326-Ab-2;
GM-Tg-mg-IP2326-Ab-1/ GM-Tg-mg-IP2326-Ab-2; GM-Tg-cynog-IP2326-Ab-1/ GM-Tg-cynog-IP2326-Ab-2;
GM-Tg-felg-IP2326-Ab-1/ GM-Tg-felg-IP2326-Ab-2; GM-Tg-cang-IP2326-Ab-1/ GM-Tg-cang-IP2326-Ab-2;
GM-Tg-bovg-IP2326-Ab-1/ GM-Tg-bovg-IP2326-Ab-2; GM-Tg-equg-IP2326-Ab-1/ GM-Tg-equg-IP2326-Ab-2
Products NameAnti-ZNRF4 monoclonal antibody
Formatmab
Target NameZNRF4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-ZNRF4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2326-Ag-1Recombinant multi-species ZNRF4/ RNF204/ SPERIZIN protein


    Target information

    Target IDGM-IP2326
    Target NameZNRF4
    Gene ID148066,20834,301127,695996,485029,105261107,517394,111774187
    Gene Symbol and Synonyms1700094M01Rik,RNF204,SPERIZIN,spzn,Ssrzf1,ZNRF4
    Uniprot AccessionQ8WWF5
    Uniprot Entry NameZNRF4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000105428
    Target ClassificationN/A

    The target: ZNRF4, gene name: ZNRF4, also named as RNF204, SPERIZIN, Ssrzf1, spzn. Predicted to enable ubiquitin protein ligase activity. Involved in ubiquitin-dependent protein catabolic process. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.