Anti-ABLIM3 monoclonal antibody

Pre-made anti-ABLIM3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ABLIM3/ABLIM3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2329-Ab-1/ GM-Tg-hg-IP2329-Ab-2Anti-Human ABLIM3 monoclonal antibodyHuman
GM-Tg-rg-IP2329-Ab-1/ GM-Tg-rg-IP2329-Ab-2Anti-Rat ABLIM3 monoclonal antibodyRat
GM-Tg-mg-IP2329-Ab-1/ GM-Tg-mg-IP2329-Ab-2Anti-Mouse ABLIM3 monoclonal antibodyMouse
GM-Tg-cynog-IP2329-Ab-1/ GM-Tg-cynog-IP2329-Ab-2Anti-Cynomolgus/ Rhesus macaque ABLIM3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2329-Ab-1/ GM-Tg-felg-IP2329-Ab-2Anti-Feline ABLIM3 monoclonal antibodyFeline
GM-Tg-cang-IP2329-Ab-1/ GM-Tg-cang-IP2329-Ab-2Anti-Canine ABLIM3 monoclonal antibodyCanine
GM-Tg-bovg-IP2329-Ab-1/ GM-Tg-bovg-IP2329-Ab-2Anti-Bovine ABLIM3 monoclonal antibodyBovine
GM-Tg-equg-IP2329-Ab-1/ GM-Tg-equg-IP2329-Ab-2Anti-Equine ABLIM3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2329-Ab-1/ GM-Tg-hg-IP2329-Ab-2; GM-Tg-rg-IP2329-Ab-1/ GM-Tg-rg-IP2329-Ab-2;
GM-Tg-mg-IP2329-Ab-1/ GM-Tg-mg-IP2329-Ab-2; GM-Tg-cynog-IP2329-Ab-1/ GM-Tg-cynog-IP2329-Ab-2;
GM-Tg-felg-IP2329-Ab-1/ GM-Tg-felg-IP2329-Ab-2; GM-Tg-cang-IP2329-Ab-1/ GM-Tg-cang-IP2329-Ab-2;
GM-Tg-bovg-IP2329-Ab-1/ GM-Tg-bovg-IP2329-Ab-2; GM-Tg-equg-IP2329-Ab-1/ GM-Tg-equg-IP2329-Ab-2
Products NameAnti-ABLIM3 monoclonal antibody
Formatmab
Target NameABLIM3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-ABLIM3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2329-Ag-1Recombinant multi-species ABLM3/ ABLIM3/ HMFN1661 protein


    Target information

    Target IDGM-IP2329
    Target NameABLIM3
    Gene ID22885,319713,307395,709180,612309,101086700,613794,100071715
    Gene Symbol and SynonymsABLIM3,D930036B08Rik,HMFN1661,RGD1565118
    Uniprot AccessionO94929
    Uniprot Entry NameABLM3_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000173210
    Target ClassificationN/A

    The target: ABLIM3, gene name: ABLIM3, also named as HMFN1661. This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients. [provided by RefSeq, Sep 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.