- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-ARHGAP24 monoclonal antibody
Pre-made anti-ARHGAP24 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ARHGAP24/ARHGAP24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2349-Ab-1/ GM-Tg-hg-IP2349-Ab-2 | Anti-Human ARHGAP24 monoclonal antibody | Human |
| GM-Tg-rg-IP2349-Ab-1/ GM-Tg-rg-IP2349-Ab-2 | Anti-Rat ARHGAP24 monoclonal antibody | Rat |
| GM-Tg-mg-IP2349-Ab-1/ GM-Tg-mg-IP2349-Ab-2 | Anti-Mouse ARHGAP24 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2349-Ab-1/ GM-Tg-cynog-IP2349-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ARHGAP24 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2349-Ab-1/ GM-Tg-felg-IP2349-Ab-2 | Anti-Feline ARHGAP24 monoclonal antibody | Feline |
| GM-Tg-cang-IP2349-Ab-1/ GM-Tg-cang-IP2349-Ab-2 | Anti-Canine ARHGAP24 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2349-Ab-1/ GM-Tg-bovg-IP2349-Ab-2 | Anti-Bovine ARHGAP24 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2349-Ab-1/ GM-Tg-equg-IP2349-Ab-2 | Anti-Equine ARHGAP24 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2349-Ab-1/ GM-Tg-hg-IP2349-Ab-2; GM-Tg-rg-IP2349-Ab-1/ GM-Tg-rg-IP2349-Ab-2; GM-Tg-mg-IP2349-Ab-1/ GM-Tg-mg-IP2349-Ab-2; GM-Tg-cynog-IP2349-Ab-1/ GM-Tg-cynog-IP2349-Ab-2; GM-Tg-felg-IP2349-Ab-1/ GM-Tg-felg-IP2349-Ab-2; GM-Tg-cang-IP2349-Ab-1/ GM-Tg-cang-IP2349-Ab-2; GM-Tg-bovg-IP2349-Ab-1/ GM-Tg-bovg-IP2349-Ab-2; GM-Tg-equg-IP2349-Ab-1/ GM-Tg-equg-IP2349-Ab-2 |
| Products Name | Anti-ARHGAP24 monoclonal antibody |
| Format | mab |
| Target Name | ARHGAP24 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ARHGAP24 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2349-Ag-1 | Recombinant multi-species RHG24/ ARHGAP24/ FILGAP protein |
| ORF Viral Vector | pGMLP004338 | human ARHGAP24 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004338 | human ARHGAP24 Lentivirus particle |
| ORF Viral Vector | pGMLPm003880 | mouse Arhgap24 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003880 | mouse Arhgap24 Lentivirus particle |
Target information
| Target ID | GM-IP2349 |
| Target Name | ARHGAP24 |
| Gene ID | 83478,231532,305156,699614,478463,101080454,539902,100052555 |
| Gene Symbol and Synonyms | 0610025G21Rik,ARHGAP24,DR-NR#2,FILGAP,p73,p73RhoGAP,RC-GAP72,RCGAP72 |
| Uniprot Accession | Q8N264,Q5U2Z7 |
| Uniprot Entry Name | RHG24_HUMAN,RHG24_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000138639 |
| Target Classification | N/A |
The target: ARHGAP24, gene name: ARHGAP24, also named as FILGAP, RC-GAP72, RCGAP72, p73, p73RhoGAP. This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
