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Anti-ASPM monoclonal antibody
Pre-made anti-ASPM monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ASPM/ASPM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2363-Ab-1/ GM-Tg-hg-IP2363-Ab-2 | Anti-Human ASPM monoclonal antibody | Human |
| GM-Tg-rg-IP2363-Ab-1/ GM-Tg-rg-IP2363-Ab-2 | Anti-Rat ASPM monoclonal antibody | Rat |
| GM-Tg-mg-IP2363-Ab-1/ GM-Tg-mg-IP2363-Ab-2 | Anti-Mouse ASPM monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2363-Ab-1/ GM-Tg-cynog-IP2363-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ASPM monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2363-Ab-1/ GM-Tg-felg-IP2363-Ab-2 | Anti-Feline ASPM monoclonal antibody | Feline |
| GM-Tg-cang-IP2363-Ab-1/ GM-Tg-cang-IP2363-Ab-2 | Anti-Canine ASPM monoclonal antibody | Canine |
| GM-Tg-bovg-IP2363-Ab-1/ GM-Tg-bovg-IP2363-Ab-2 | Anti-Bovine ASPM monoclonal antibody | Bovine |
| GM-Tg-equg-IP2363-Ab-1/ GM-Tg-equg-IP2363-Ab-2 | Anti-Equine ASPM monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2363-Ab-1/ GM-Tg-hg-IP2363-Ab-2; GM-Tg-rg-IP2363-Ab-1/ GM-Tg-rg-IP2363-Ab-2; GM-Tg-mg-IP2363-Ab-1/ GM-Tg-mg-IP2363-Ab-2; GM-Tg-cynog-IP2363-Ab-1/ GM-Tg-cynog-IP2363-Ab-2; GM-Tg-felg-IP2363-Ab-1/ GM-Tg-felg-IP2363-Ab-2; GM-Tg-cang-IP2363-Ab-1/ GM-Tg-cang-IP2363-Ab-2; GM-Tg-bovg-IP2363-Ab-1/ GM-Tg-bovg-IP2363-Ab-2; GM-Tg-equg-IP2363-Ab-1/ GM-Tg-equg-IP2363-Ab-2 |
| Products Name | Anti-ASPM monoclonal antibody |
| Format | mab |
| Target Name | ASPM |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ASPM monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2363-Ag-1 | Recombinant multi-species ASPM/ ASP/ Calmbp1 protein |
Target information
| Target ID | GM-IP2363 |
| Target Name | ASPM |
| Gene ID | 259266,12316,289054,711153,480009,493695,534849,100060893 |
| Gene Symbol and Synonyms | ASP,ASPM,Calmbp1,D330028K02Rik,MCPH5,Sha1 |
| Uniprot Accession | Q8IZT6,P62292,P62286,P62288,P62285 |
| Uniprot Entry Name | ASPM_HUMAN,ASPM_MACMU,ASPM_FELCA,ASPM_CANLF,ASPM_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000066279 |
| Target Classification | N/A |
The target: ASPM, gene name: ASPM, also named as ASP, Calmbp1, MCPH5. This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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