Anti-CCDC154 monoclonal antibody

Pre-made anti-CCDC154 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CCDC154/CCDC154 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2407-Ab-1/ GM-Tg-hg-IP2407-Ab-2Anti-Human CCDC154 monoclonal antibodyHuman
GM-Tg-rg-IP2407-Ab-1/ GM-Tg-rg-IP2407-Ab-2Anti-Rat CCDC154 monoclonal antibodyRat
GM-Tg-mg-IP2407-Ab-1/ GM-Tg-mg-IP2407-Ab-2Anti-Mouse CCDC154 monoclonal antibodyMouse
GM-Tg-cynog-IP2407-Ab-1/ GM-Tg-cynog-IP2407-Ab-2Anti-Cynomolgus/ Rhesus macaque CCDC154 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2407-Ab-1/ GM-Tg-felg-IP2407-Ab-2Anti-Feline CCDC154 monoclonal antibodyFeline
GM-Tg-cang-IP2407-Ab-1/ GM-Tg-cang-IP2407-Ab-2Anti-Canine CCDC154 monoclonal antibodyCanine
GM-Tg-bovg-IP2407-Ab-1/ GM-Tg-bovg-IP2407-Ab-2Anti-Bovine CCDC154 monoclonal antibodyBovine
GM-Tg-equg-IP2407-Ab-1/ GM-Tg-equg-IP2407-Ab-2Anti-Equine CCDC154 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2407-Ab-1/ GM-Tg-hg-IP2407-Ab-2; GM-Tg-rg-IP2407-Ab-1/ GM-Tg-rg-IP2407-Ab-2;
GM-Tg-mg-IP2407-Ab-1/ GM-Tg-mg-IP2407-Ab-2; GM-Tg-cynog-IP2407-Ab-1/ GM-Tg-cynog-IP2407-Ab-2;
GM-Tg-felg-IP2407-Ab-1/ GM-Tg-felg-IP2407-Ab-2; GM-Tg-cang-IP2407-Ab-1/ GM-Tg-cang-IP2407-Ab-2;
GM-Tg-bovg-IP2407-Ab-1/ GM-Tg-bovg-IP2407-Ab-2; GM-Tg-equg-IP2407-Ab-1/ GM-Tg-equg-IP2407-Ab-2
Products NameAnti-CCDC154 monoclonal antibody
Formatmab
Target NameCCDC154
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CCDC154 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2407-Ag-1Recombinant multi-species CC154/ CCDC154/ C16orf29 protein


    Target information

    Target IDGM-IP2407
    Target NameCCDC154
    Gene ID645811,207209,287131,100429196,100685080,101087545,101904581,100067669
    Gene Symbol and SynonymsC16orf29,CCDC154,Ccdc157,Gm317,ntl,RGD1559998
    Uniprot AccessionA6NI56
    Uniprot Entry NameCC154_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197599
    Target ClassificationN/A

    The target: CCDC154, gene name: CCDC154, also named as C16orf29. Predicted to be involved in bone mineralization involved in bone maturation. Predicted to act upstream of or within bone resorption; odontogenesis of dentin-containing tooth; and tooth eruption. Predicted to be located in early endosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.