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Anti-CCT3 monoclonal antibody
Pre-made anti-CCT3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CCT3/CCT3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2418-Ab-1/ GM-Tg-hg-IP2418-Ab-2 | Anti-Human CCT3 monoclonal antibody | Human |
| GM-Tg-rg-IP2418-Ab-1/ GM-Tg-rg-IP2418-Ab-2 | Anti-Rat CCT3 monoclonal antibody | Rat |
| GM-Tg-mg-IP2418-Ab-1/ GM-Tg-mg-IP2418-Ab-2 | Anti-Mouse CCT3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2418-Ab-1/ GM-Tg-cynog-IP2418-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCT3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2418-Ab-1/ GM-Tg-felg-IP2418-Ab-2 | Anti-Feline CCT3 monoclonal antibody | Feline |
| GM-Tg-cang-IP2418-Ab-1/ GM-Tg-cang-IP2418-Ab-2 | Anti-Canine CCT3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2418-Ab-1/ GM-Tg-bovg-IP2418-Ab-2 | Anti-Bovine CCT3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2418-Ab-1/ GM-Tg-equg-IP2418-Ab-2 | Anti-Equine CCT3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2418-Ab-1/ GM-Tg-hg-IP2418-Ab-2; GM-Tg-rg-IP2418-Ab-1/ GM-Tg-rg-IP2418-Ab-2; GM-Tg-mg-IP2418-Ab-1/ GM-Tg-mg-IP2418-Ab-2; GM-Tg-cynog-IP2418-Ab-1/ GM-Tg-cynog-IP2418-Ab-2; GM-Tg-felg-IP2418-Ab-1/ GM-Tg-felg-IP2418-Ab-2; GM-Tg-cang-IP2418-Ab-1/ GM-Tg-cang-IP2418-Ab-2; GM-Tg-bovg-IP2418-Ab-1/ GM-Tg-bovg-IP2418-Ab-2; GM-Tg-equg-IP2418-Ab-1/ GM-Tg-equg-IP2418-Ab-2 |
| Products Name | Anti-CCT3 monoclonal antibody |
| Format | mab |
| Target Name | CCT3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CCT3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2418-Ag-1 | Recombinant multi-species TCPG/ CCT3/ CCT-gamma protein |
| ORF Viral Vector | vGMLP001376 | human CCT3 Lentivirus particle |
| ORF Viral Vector | pGMLP001376 | human CCT3 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm005010 | mouse Cct3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005010 | mouse Cct3 Lentivirus particle |
Target information
| Target ID | GM-IP2418 |
| Target Name | CCT3 |
| Gene ID | 7203,12462,295230,718374,480123,101083059,504735,100057839 |
| Gene Symbol and Synonyms | CCT-gamma,CCT3,CCTG,PIG48,TCP-1-gamma,Tcp1-rs3,TriC-P5,TRIC5 |
| Uniprot Accession | P49368,Q6P502,Q3T0K2 |
| Uniprot Entry Name | TCPG_HUMAN,TCPG_RAT,TCPG_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000163468 |
| Target Classification | N/A |
The target: CCT3, gene name: CCT3, also named as CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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