Anti-CHCHD7 monoclonal antibody

Pre-made anti-CHCHD7 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CHCHD7/CHCHD7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2427-Ab-1/ GM-Tg-hg-IP2427-Ab-2Anti-Human CHCHD7 monoclonal antibodyHuman
GM-Tg-rg-IP2427-Ab-1/ GM-Tg-rg-IP2427-Ab-2Anti-Rat CHCHD7 monoclonal antibodyRat
GM-Tg-mg-IP2427-Ab-1/ GM-Tg-mg-IP2427-Ab-2Anti-Mouse CHCHD7 monoclonal antibodyMouse
GM-Tg-cynog-IP2427-Ab-1/ GM-Tg-cynog-IP2427-Ab-2Anti-Cynomolgus/ Rhesus macaque CHCHD7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2427-Ab-1/ GM-Tg-felg-IP2427-Ab-2Anti-Feline CHCHD7 monoclonal antibodyFeline
GM-Tg-cang-IP2427-Ab-1/ GM-Tg-cang-IP2427-Ab-2Anti-Canine CHCHD7 monoclonal antibodyCanine
GM-Tg-bovg-IP2427-Ab-1/ GM-Tg-bovg-IP2427-Ab-2Anti-Bovine CHCHD7 monoclonal antibodyBovine
GM-Tg-equg-IP2427-Ab-1/ GM-Tg-equg-IP2427-Ab-2Anti-Equine CHCHD7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2427-Ab-1/ GM-Tg-hg-IP2427-Ab-2; GM-Tg-rg-IP2427-Ab-1/ GM-Tg-rg-IP2427-Ab-2;
GM-Tg-mg-IP2427-Ab-1/ GM-Tg-mg-IP2427-Ab-2; GM-Tg-cynog-IP2427-Ab-1/ GM-Tg-cynog-IP2427-Ab-2;
GM-Tg-felg-IP2427-Ab-1/ GM-Tg-felg-IP2427-Ab-2; GM-Tg-cang-IP2427-Ab-1/ GM-Tg-cang-IP2427-Ab-2;
GM-Tg-bovg-IP2427-Ab-1/ GM-Tg-bovg-IP2427-Ab-2; GM-Tg-equg-IP2427-Ab-1/ GM-Tg-equg-IP2427-Ab-2
Products NameAnti-CHCHD7 monoclonal antibody
Formatmab
Target NameCHCHD7
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CHCHD7 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2427-Ag-1Recombinant multi-species CHCH7/ CHCHD7/ COX23 protein


    Target information

    Target IDGM-IP2427
    Target NameCHCHD7
    Gene ID79145,66433,684258,699551,609282,101097868,616237,100629901
    Gene Symbol and Synonyms1810049H20Rik,CHCHD7,COX23
    Uniprot AccessionQ9BUK0,Q17Q91
    Uniprot Entry NameCHCH7_HUMAN,CHCH7_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000170791
    Target ClassificationTumor-associated antigen (TAA)

    The target: CHCHD7, gene name: CHCHD7, also named as COX23. Predicted to be located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.