Anti-CLIC5 monoclonal antibody

Pre-made anti-CLIC5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CLIC5/CLIC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2430-Ab-1/ GM-Tg-hg-IP2430-Ab-2Anti-Human CLIC5 monoclonal antibodyHuman
GM-Tg-rg-IP2430-Ab-1/ GM-Tg-rg-IP2430-Ab-2Anti-Rat CLIC5 monoclonal antibodyRat
GM-Tg-mg-IP2430-Ab-1/ GM-Tg-mg-IP2430-Ab-2Anti-Mouse CLIC5 monoclonal antibodyMouse
GM-Tg-cynog-IP2430-Ab-1/ GM-Tg-cynog-IP2430-Ab-2Anti-Cynomolgus/ Rhesus macaque CLIC5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2430-Ab-1/ GM-Tg-felg-IP2430-Ab-2Anti-Feline CLIC5 monoclonal antibodyFeline
GM-Tg-cang-IP2430-Ab-1/ GM-Tg-cang-IP2430-Ab-2Anti-Canine CLIC5 monoclonal antibodyCanine
GM-Tg-bovg-IP2430-Ab-1/ GM-Tg-bovg-IP2430-Ab-2Anti-Bovine CLIC5 monoclonal antibodyBovine
GM-Tg-equg-IP2430-Ab-1/ GM-Tg-equg-IP2430-Ab-2Anti-Equine CLIC5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2430-Ab-1/ GM-Tg-hg-IP2430-Ab-2; GM-Tg-rg-IP2430-Ab-1/ GM-Tg-rg-IP2430-Ab-2;
GM-Tg-mg-IP2430-Ab-1/ GM-Tg-mg-IP2430-Ab-2; GM-Tg-cynog-IP2430-Ab-1/ GM-Tg-cynog-IP2430-Ab-2;
GM-Tg-felg-IP2430-Ab-1/ GM-Tg-felg-IP2430-Ab-2; GM-Tg-cang-IP2430-Ab-1/ GM-Tg-cang-IP2430-Ab-2;
GM-Tg-bovg-IP2430-Ab-1/ GM-Tg-bovg-IP2430-Ab-2; GM-Tg-equg-IP2430-Ab-1/ GM-Tg-equg-IP2430-Ab-2
Products NameAnti-CLIC5 monoclonal antibody
Formatmab
Target NameCLIC5
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CLIC5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2430-Ag-1Recombinant multi-species CLIC5/ DFNB102/ DFNB103 protein


    Target information

    Target IDGM-IP2430
    Target NameCLIC5
    Gene ID53405,224796,94272,703565,481822,101099207,281696,100055661
    Gene Symbol and Synonyms5730531E12Rik,B330005L24,CLIC5,DFNB102,DFNB103,Gm322,jbg,MST130,MSTP130,nmf318
    Uniprot AccessionQ9NZA1,Q9EPT8,P35526
    Uniprot Entry NameCLIC5_HUMAN,CLIC5_RAT,CLIC5_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000112782
    Target ClassificationN/A

    The target: CLIC5, gene name: CLIC5, also named as DFNB102, DFNB103, MST130, MSTP130. This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.