Anti-CORO2B monoclonal antibody

Pre-made anti-CORO2B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CORO2B/CORO2B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2434-Ab-1/ GM-Tg-hg-IP2434-Ab-2Anti-Human CORO2B monoclonal antibodyHuman
GM-Tg-rg-IP2434-Ab-1/ GM-Tg-rg-IP2434-Ab-2Anti-Rat CORO2B monoclonal antibodyRat
GM-Tg-mg-IP2434-Ab-1/ GM-Tg-mg-IP2434-Ab-2Anti-Mouse CORO2B monoclonal antibodyMouse
GM-Tg-cynog-IP2434-Ab-1/ GM-Tg-cynog-IP2434-Ab-2Anti-Cynomolgus/ Rhesus macaque CORO2B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2434-Ab-1/ GM-Tg-felg-IP2434-Ab-2Anti-Feline CORO2B monoclonal antibodyFeline
GM-Tg-cang-IP2434-Ab-1/ GM-Tg-cang-IP2434-Ab-2Anti-Canine CORO2B monoclonal antibodyCanine
GM-Tg-bovg-IP2434-Ab-1/ GM-Tg-bovg-IP2434-Ab-2Anti-Bovine CORO2B monoclonal antibodyBovine
GM-Tg-equg-IP2434-Ab-1/ GM-Tg-equg-IP2434-Ab-2Anti-Equine CORO2B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2434-Ab-1/ GM-Tg-hg-IP2434-Ab-2; GM-Tg-rg-IP2434-Ab-1/ GM-Tg-rg-IP2434-Ab-2;
GM-Tg-mg-IP2434-Ab-1/ GM-Tg-mg-IP2434-Ab-2; GM-Tg-cynog-IP2434-Ab-1/ GM-Tg-cynog-IP2434-Ab-2;
GM-Tg-felg-IP2434-Ab-1/ GM-Tg-felg-IP2434-Ab-2; GM-Tg-cang-IP2434-Ab-1/ GM-Tg-cang-IP2434-Ab-2;
GM-Tg-bovg-IP2434-Ab-1/ GM-Tg-bovg-IP2434-Ab-2; GM-Tg-equg-IP2434-Ab-1/ GM-Tg-equg-IP2434-Ab-2
Products NameAnti-CORO2B monoclonal antibody
Formatmab
Target NameCORO2B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CORO2B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2434-Ag-1Recombinant multi-species COR2B/ CORO2B/ CLIPINC protein


    Target information

    Target IDGM-IP2434
    Target NameCORO2B
    Gene ID10391,235431,300768,694229,487618,101099720,615274,100052637
    Gene Symbol and SynonymsCLIPINC,CORO2B,E130012P22Rik
    Uniprot AccessionQ9UQ03
    Uniprot Entry NameCOR2B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000103647
    Target ClassificationN/A

    The target: CORO2B, gene name: CORO2B, also named as CLIPINC. Enables talin binding activity and vinculin binding activity. Acts upstream of or within several processes, including negative regulation of cell-substrate adhesion; regulation of actin cytoskeleton organization; and regulation of establishment of protein localization. Located in focal adhesion. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.