Anti-CRIP1 monoclonal antibody

Pre-made anti-CRIP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CRIP1/CRIP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2437-Ab-1/ GM-Tg-hg-IP2437-Ab-2Anti-Human CRIP1 monoclonal antibodyHuman
GM-Tg-rg-IP2437-Ab-1/ GM-Tg-rg-IP2437-Ab-2Anti-Rat CRIP1 monoclonal antibodyRat
GM-Tg-mg-IP2437-Ab-1/ GM-Tg-mg-IP2437-Ab-2Anti-Mouse CRIP1 monoclonal antibodyMouse
GM-Tg-cynog-IP2437-Ab-1/ GM-Tg-cynog-IP2437-Ab-2Anti-Cynomolgus/ Rhesus macaque CRIP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2437-Ab-1/ GM-Tg-felg-IP2437-Ab-2Anti-Feline CRIP1 monoclonal antibodyFeline
GM-Tg-cang-IP2437-Ab-1/ GM-Tg-cang-IP2437-Ab-2Anti-Canine CRIP1 monoclonal antibodyCanine
GM-Tg-bovg-IP2437-Ab-1/ GM-Tg-bovg-IP2437-Ab-2Anti-Bovine CRIP1 monoclonal antibodyBovine
GM-Tg-equg-IP2437-Ab-1/ GM-Tg-equg-IP2437-Ab-2Anti-Equine CRIP1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2437-Ab-1/ GM-Tg-hg-IP2437-Ab-2; GM-Tg-rg-IP2437-Ab-1/ GM-Tg-rg-IP2437-Ab-2;
GM-Tg-mg-IP2437-Ab-1/ GM-Tg-mg-IP2437-Ab-2; GM-Tg-cynog-IP2437-Ab-1/ GM-Tg-cynog-IP2437-Ab-2;
GM-Tg-felg-IP2437-Ab-1/ GM-Tg-felg-IP2437-Ab-2; GM-Tg-cang-IP2437-Ab-1/ GM-Tg-cang-IP2437-Ab-2;
GM-Tg-bovg-IP2437-Ab-1/ GM-Tg-bovg-IP2437-Ab-2; GM-Tg-equg-IP2437-Ab-1/ GM-Tg-equg-IP2437-Ab-2
Products NameAnti-CRIP1 monoclonal antibody
Formatmab
Target NameCRIP1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CRIP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2437-Ag-1Recombinant multi-species CRIP1/ CRHP/ CRIP protein
    ORF Viral VectorvGMLP000219human CRIP1 Lentivirus particle
    ORF Viral VectorpGMLP000219human CRIP1 Lentivirus plasmid
    ORF Viral VectorpGMLPm000065mouse Crip1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000065mouse Crip1 Lentivirus particle


    Target information

    Target IDGM-IP2437
    Target NameCRIP1
    Gene ID1396,12925,691657,699632,612713,101101478,574093,100630592
    Gene Symbol and SynonymsCRHP,CRIP,CRIP1,CRP-1,CRP1
    Uniprot AccessionP50238,P63255,Q56K04
    Uniprot Entry NameCRIP1_HUMAN,CRIP1_RAT,CRIP1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000213145
    Target ClassificationN/A

    The target: CRIP1, gene name: CRIP1, also named as CRHP, CRIP, CRP-1, CRP1. Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.