Anti-DENND6B monoclonal antibody

Pre-made anti-DENND6B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DENND6B/DENND6B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2453-Ab-1/ GM-Tg-hg-IP2453-Ab-2Anti-Human DENND6B monoclonal antibodyHuman
GM-Tg-rg-IP2453-Ab-1/ GM-Tg-rg-IP2453-Ab-2Anti-Rat DENND6B monoclonal antibodyRat
GM-Tg-mg-IP2453-Ab-1/ GM-Tg-mg-IP2453-Ab-2Anti-Mouse DENND6B monoclonal antibodyMouse
GM-Tg-cynog-IP2453-Ab-1/ GM-Tg-cynog-IP2453-Ab-2Anti-Cynomolgus/ Rhesus macaque DENND6B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2453-Ab-1/ GM-Tg-felg-IP2453-Ab-2Anti-Feline DENND6B monoclonal antibodyFeline
GM-Tg-cang-IP2453-Ab-1/ GM-Tg-cang-IP2453-Ab-2Anti-Canine DENND6B monoclonal antibodyCanine
GM-Tg-bovg-IP2453-Ab-1/ GM-Tg-bovg-IP2453-Ab-2Anti-Bovine DENND6B monoclonal antibodyBovine
GM-Tg-equg-IP2453-Ab-1/ GM-Tg-equg-IP2453-Ab-2Anti-Equine DENND6B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2453-Ab-1/ GM-Tg-hg-IP2453-Ab-2; GM-Tg-rg-IP2453-Ab-1/ GM-Tg-rg-IP2453-Ab-2;
GM-Tg-mg-IP2453-Ab-1/ GM-Tg-mg-IP2453-Ab-2; GM-Tg-cynog-IP2453-Ab-1/ GM-Tg-cynog-IP2453-Ab-2;
GM-Tg-felg-IP2453-Ab-1/ GM-Tg-felg-IP2453-Ab-2; GM-Tg-cang-IP2453-Ab-1/ GM-Tg-cang-IP2453-Ab-2;
GM-Tg-bovg-IP2453-Ab-1/ GM-Tg-bovg-IP2453-Ab-2; GM-Tg-equg-IP2453-Ab-1/ GM-Tg-equg-IP2453-Ab-2
Products NameAnti-DENND6B monoclonal antibody
Formatmab
Target NameDENND6B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DENND6B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2453-Ag-1Recombinant multi-species DEN6B/ DENND6B/ AFI1B protein


    Target information

    Target IDGM-IP2453
    Target NameDENND6B
    Gene ID414918,69440,362983,715877,481192,101081648,100139352,100056442
    Gene Symbol and Synonyms1700027J05Rik,AFI1B,DENND6B,FAM116B,RGD1308012
    Uniprot AccessionQ8NEG7
    Uniprot Entry NameDEN6B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000205593
    Target ClassificationN/A

    The target: DENND6B, gene name: DENND6B, also named as AFI1B, FAM116B. Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytosol. Predicted to be active in recycling endosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.