Anti-DNAH17 monoclonal antibody

Pre-made anti-DNAH17 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DNAH17/DNAH17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2457-Ab-1/ GM-Tg-hg-IP2457-Ab-2Anti-Human DNAH17 monoclonal antibodyHuman
GM-Tg-rg-IP2457-Ab-1/ GM-Tg-rg-IP2457-Ab-2Anti-Rat DNAH17 monoclonal antibodyRat
GM-Tg-mg-IP2457-Ab-1/ GM-Tg-mg-IP2457-Ab-2Anti-Mouse DNAH17 monoclonal antibodyMouse
GM-Tg-cynog-IP2457-Ab-1/ GM-Tg-cynog-IP2457-Ab-2Anti-Cynomolgus/ Rhesus macaque DNAH17 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2457-Ab-1/ GM-Tg-felg-IP2457-Ab-2Anti-Feline DNAH17 monoclonal antibodyFeline
GM-Tg-cang-IP2457-Ab-1/ GM-Tg-cang-IP2457-Ab-2Anti-Canine DNAH17 monoclonal antibodyCanine
GM-Tg-bovg-IP2457-Ab-1/ GM-Tg-bovg-IP2457-Ab-2Anti-Bovine DNAH17 monoclonal antibodyBovine
GM-Tg-equg-IP2457-Ab-1/ GM-Tg-equg-IP2457-Ab-2Anti-Equine DNAH17 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2457-Ab-1/ GM-Tg-hg-IP2457-Ab-2; GM-Tg-rg-IP2457-Ab-1/ GM-Tg-rg-IP2457-Ab-2;
GM-Tg-mg-IP2457-Ab-1/ GM-Tg-mg-IP2457-Ab-2; GM-Tg-cynog-IP2457-Ab-1/ GM-Tg-cynog-IP2457-Ab-2;
GM-Tg-felg-IP2457-Ab-1/ GM-Tg-felg-IP2457-Ab-2; GM-Tg-cang-IP2457-Ab-1/ GM-Tg-cang-IP2457-Ab-2;
GM-Tg-bovg-IP2457-Ab-1/ GM-Tg-bovg-IP2457-Ab-2; GM-Tg-equg-IP2457-Ab-1/ GM-Tg-equg-IP2457-Ab-2
Products NameAnti-DNAH17 monoclonal antibody
Formatmab
Target NameDNAH17
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DNAH17 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2457-Ag-1Recombinant multi-species DYH17/ DNAH17/ DNAHL1 protein


    Target information

    Target IDGM-IP2457
    Target NameDNAH17
    Gene ID8632,69926,287845,715774,475921,101082357,788092,100057640
    Gene Symbol and Synonyms2810003K23Rik,DNAH17,Dnahc11,Dnahc17,Dnahcl1,DNAHL1,DNEL2,Gm1178,mKIAA3028,SPGF39
    Uniprot AccessionQ9UFH2
    Uniprot Entry NameDYH17_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000187775
    Target ClassificationN/A

    The target: DNAH17, gene name: DNAH17, also named as DNAHL1, DNEL2. Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. DNAH17 is a heavy chain associated with axonemal dynein (Milisav and Affara, 1998 [PubMed 9545504]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.