Anti-DNAJC6 monoclonal antibody

Pre-made anti-DNAJC6 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DNAJC6/DNAJC6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2460-Ab-1/ GM-Tg-hg-IP2460-Ab-2Anti-Human DNAJC6 monoclonal antibodyHuman
GM-Tg-rg-IP2460-Ab-1/ GM-Tg-rg-IP2460-Ab-2Anti-Rat DNAJC6 monoclonal antibodyRat
GM-Tg-mg-IP2460-Ab-1/ GM-Tg-mg-IP2460-Ab-2Anti-Mouse DNAJC6 monoclonal antibodyMouse
GM-Tg-cynog-IP2460-Ab-1/ GM-Tg-cynog-IP2460-Ab-2Anti-Cynomolgus/ Rhesus macaque DNAJC6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2460-Ab-1/ GM-Tg-felg-IP2460-Ab-2Anti-Feline DNAJC6 monoclonal antibodyFeline
GM-Tg-cang-IP2460-Ab-1/ GM-Tg-cang-IP2460-Ab-2Anti-Canine DNAJC6 monoclonal antibodyCanine
GM-Tg-bovg-IP2460-Ab-1/ GM-Tg-bovg-IP2460-Ab-2Anti-Bovine DNAJC6 monoclonal antibodyBovine
GM-Tg-equg-IP2460-Ab-1/ GM-Tg-equg-IP2460-Ab-2Anti-Equine DNAJC6 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2460-Ab-1/ GM-Tg-hg-IP2460-Ab-2; GM-Tg-rg-IP2460-Ab-1/ GM-Tg-rg-IP2460-Ab-2;
GM-Tg-mg-IP2460-Ab-1/ GM-Tg-mg-IP2460-Ab-2; GM-Tg-cynog-IP2460-Ab-1/ GM-Tg-cynog-IP2460-Ab-2;
GM-Tg-felg-IP2460-Ab-1/ GM-Tg-felg-IP2460-Ab-2; GM-Tg-cang-IP2460-Ab-1/ GM-Tg-cang-IP2460-Ab-2;
GM-Tg-bovg-IP2460-Ab-1/ GM-Tg-bovg-IP2460-Ab-2; GM-Tg-equg-IP2460-Ab-1/ GM-Tg-equg-IP2460-Ab-2
Products NameAnti-DNAJC6 monoclonal antibody
Formatmab
Target NameDNAJC6
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DNAJC6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2460-Ag-1Recombinant multi-species AUXI/ DNAJC6/ DJC6 protein


    Target information

    Target IDGM-IP2460
    Target NameDNAJC6
    Gene ID9829,72685,313409,698682,489553,101084891,317659,100069605
    Gene Symbol and Synonyms2810027M23Rik,DJC6,DNAJC6,mKIAA0473,PARK19
    Uniprot AccessionO75061,Q27974
    Uniprot Entry NameAUXI_HUMAN,AUXI_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000116675
    Target ClassificationN/A

    The target: DNAJC6, gene name: DNAJC6, also named as DJC6, PARK19. DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.