Anti-DUS1L monoclonal antibody

Pre-made anti-DUS1L monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DUS1L/DUS1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2464-Ab-1/ GM-Tg-hg-IP2464-Ab-2Anti-Human DUS1L monoclonal antibodyHuman
GM-Tg-rg-IP2464-Ab-1/ GM-Tg-rg-IP2464-Ab-2Anti-Rat DUS1L monoclonal antibodyRat
GM-Tg-mg-IP2464-Ab-1/ GM-Tg-mg-IP2464-Ab-2Anti-Mouse DUS1L monoclonal antibodyMouse
GM-Tg-cynog-IP2464-Ab-1/ GM-Tg-cynog-IP2464-Ab-2Anti-Cynomolgus/ Rhesus macaque DUS1L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2464-Ab-1/ GM-Tg-felg-IP2464-Ab-2Anti-Feline DUS1L monoclonal antibodyFeline
GM-Tg-cang-IP2464-Ab-1/ GM-Tg-cang-IP2464-Ab-2Anti-Canine DUS1L monoclonal antibodyCanine
GM-Tg-bovg-IP2464-Ab-1/ GM-Tg-bovg-IP2464-Ab-2Anti-Bovine DUS1L monoclonal antibodyBovine
GM-Tg-equg-IP2464-Ab-1/ GM-Tg-equg-IP2464-Ab-2Anti-Equine DUS1L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2464-Ab-1/ GM-Tg-hg-IP2464-Ab-2; GM-Tg-rg-IP2464-Ab-1/ GM-Tg-rg-IP2464-Ab-2;
GM-Tg-mg-IP2464-Ab-1/ GM-Tg-mg-IP2464-Ab-2; GM-Tg-cynog-IP2464-Ab-1/ GM-Tg-cynog-IP2464-Ab-2;
GM-Tg-felg-IP2464-Ab-1/ GM-Tg-felg-IP2464-Ab-2; GM-Tg-cang-IP2464-Ab-1/ GM-Tg-cang-IP2464-Ab-2;
GM-Tg-bovg-IP2464-Ab-1/ GM-Tg-bovg-IP2464-Ab-2; GM-Tg-equg-IP2464-Ab-1/ GM-Tg-equg-IP2464-Ab-2
Products NameAnti-DUS1L monoclonal antibody
Formatmab
Target NameDUS1L
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DUS1L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2464-Ag-1Recombinant multi-species DUS1L/ DUS1/ PP3111 protein


    Target information

    Target IDGM-IP2464
    Target NameDUS1L
    Gene ID64118,68730,246185,715662,475927,101081268,617998,100057354
    Gene Symbol and Synonyms1110032N12Rik,DUS1,DUS1L,PP3111,x85
    Uniprot AccessionQ6P1R4,Q8K582
    Uniprot Entry NameDUS1L_HUMAN,DUS1L_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169718
    Target ClassificationN/A

    The target: DUS1L, gene name: DUS1L, also named as DUS1, PP3111. Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.