Anti-EPB41L4A monoclonal antibody
Pre-made anti-EPB41L4A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP2476-Ab-1/ GM-Tg-hg-IP2476-Ab-2 | Anti-Human EPB41L4A monoclonal antibody | Human |
GM-Tg-rg-IP2476-Ab-1/ GM-Tg-rg-IP2476-Ab-2 | Anti-Rat EPB41L4A monoclonal antibody | Rat |
GM-Tg-mg-IP2476-Ab-1/ GM-Tg-mg-IP2476-Ab-2 | Anti-Mouse EPB41L4A monoclonal antibody | Mouse |
GM-Tg-cynog-IP2476-Ab-1/ GM-Tg-cynog-IP2476-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EPB41L4A monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP2476-Ab-1/ GM-Tg-felg-IP2476-Ab-2 | Anti-Feline EPB41L4A monoclonal antibody | Feline |
GM-Tg-cang-IP2476-Ab-1/ GM-Tg-cang-IP2476-Ab-2 | Anti-Canine EPB41L4A monoclonal antibody | Canine |
GM-Tg-bovg-IP2476-Ab-1/ GM-Tg-bovg-IP2476-Ab-2 | Anti-Bovine EPB41L4A monoclonal antibody | Bovine |
GM-Tg-equg-IP2476-Ab-1/ GM-Tg-equg-IP2476-Ab-2 | Anti-Equine EPB41L4A monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP2476-Ab-1/ GM-Tg-hg-IP2476-Ab-2; GM-Tg-rg-IP2476-Ab-1/ GM-Tg-rg-IP2476-Ab-2; GM-Tg-mg-IP2476-Ab-1/ GM-Tg-mg-IP2476-Ab-2; GM-Tg-cynog-IP2476-Ab-1/ GM-Tg-cynog-IP2476-Ab-2; GM-Tg-felg-IP2476-Ab-1/ GM-Tg-felg-IP2476-Ab-2; GM-Tg-cang-IP2476-Ab-1/ GM-Tg-cang-IP2476-Ab-2; GM-Tg-bovg-IP2476-Ab-1/ GM-Tg-bovg-IP2476-Ab-2; GM-Tg-equg-IP2476-Ab-1/ GM-Tg-equg-IP2476-Ab-2 |
Products Name | Anti-EPB41L4A monoclonal antibody |
Format | mab |
Target Name | EPB41L4A |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-EPB41L4A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP2476-Ag-1 | Recombinant multi-species E41LA/ EPB41L4A/ EPB41L4 protein |
Target information
Target ID | GM-IP2476 |
Target Name | EPB41L4A |
Gene ID | 64097,13824,307514,706945,479140,101095883,519867 |
Gene Symbol and Synonyms | Epb4.1l4,Epb4.1l4a,EPB41L4,EPB41L4A,NBL4 |
Uniprot Accession | Q9HCS5 |
Uniprot Entry Name | E41LA_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000129595 |
Target Classification | N/A |
The target: EPB41L4A, gene name: EPB41L4A, also named as EPB41L4, NBL4. The protein encoded by this gene is a member of the band 4.1 protein superfamily. Members of this superfamily are thought to play an important role in regulating interactions between the cytoskeleton and plasma membrane, and contain an amino terminal conserved domain that binds glycophorin C. This gene product is thought to be involved in the beta-catenin signaling pathway. [provided by RefSeq, Dec 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.