Anti-FAIM monoclonal antibody

Pre-made anti-FAIM monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FAIM/FAIM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2484-Ab-1/ GM-Tg-hg-IP2484-Ab-2Anti-Human FAIM monoclonal antibodyHuman
GM-Tg-rg-IP2484-Ab-1/ GM-Tg-rg-IP2484-Ab-2Anti-Rat FAIM monoclonal antibodyRat
GM-Tg-mg-IP2484-Ab-1/ GM-Tg-mg-IP2484-Ab-2Anti-Mouse FAIM monoclonal antibodyMouse
GM-Tg-cynog-IP2484-Ab-1/ GM-Tg-cynog-IP2484-Ab-2Anti-Cynomolgus/ Rhesus macaque FAIM monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2484-Ab-1/ GM-Tg-felg-IP2484-Ab-2Anti-Feline FAIM monoclonal antibodyFeline
GM-Tg-cang-IP2484-Ab-1/ GM-Tg-cang-IP2484-Ab-2Anti-Canine FAIM monoclonal antibodyCanine
GM-Tg-bovg-IP2484-Ab-1/ GM-Tg-bovg-IP2484-Ab-2Anti-Bovine FAIM monoclonal antibodyBovine
GM-Tg-equg-IP2484-Ab-1/ GM-Tg-equg-IP2484-Ab-2Anti-Equine FAIM monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2484-Ab-1/ GM-Tg-hg-IP2484-Ab-2; GM-Tg-rg-IP2484-Ab-1/ GM-Tg-rg-IP2484-Ab-2;
GM-Tg-mg-IP2484-Ab-1/ GM-Tg-mg-IP2484-Ab-2; GM-Tg-cynog-IP2484-Ab-1/ GM-Tg-cynog-IP2484-Ab-2;
GM-Tg-felg-IP2484-Ab-1/ GM-Tg-felg-IP2484-Ab-2; GM-Tg-cang-IP2484-Ab-1/ GM-Tg-cang-IP2484-Ab-2;
GM-Tg-bovg-IP2484-Ab-1/ GM-Tg-bovg-IP2484-Ab-2; GM-Tg-equg-IP2484-Ab-1/ GM-Tg-equg-IP2484-Ab-2
Products NameAnti-FAIM monoclonal antibody
Formatmab
Target NameFAIM
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FAIM monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2484-Ag-1Recombinant multi-species FAIM1/ FAIM protein
    ORF Viral VectorvGMLP004184human FAIM Lentivirus particle
    ORF Viral VectorpGMLP004184human FAIM Lentivirus plasmid
    ORF Viral VectorpGMLPm003301mouse Faim Lentivirus plasmid
    ORF Viral VectorvGMLPm003301mouse Faim Lentivirus particle


    Target information

    Target IDGM-IP2484
    Target NameFAIM
    Gene ID55179,716216,485687,101092137,616795,100051813
    Gene Symbol and SynonymsFAIM,FAIM1
    Uniprot AccessionQ9NVQ4,Q0IIF6
    Uniprot Entry NameFAIM1_HUMAN,FAIM1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158234
    Target ClassificationN/A

    The target: FAIM, gene name: FAIM, also named as FAIM1. The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.