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Anti-GAGE1 monoclonal antibody
Pre-made anti-GAGE1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GAGE1/GAGE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2509-Ab-1/ GM-Tg-hg-IP2509-Ab-2 | Anti-Human GAGE1 monoclonal antibody | Human |
| GM-Tg-rg-IP2509-Ab-1/ GM-Tg-rg-IP2509-Ab-2 | Anti-Rat GAGE1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2509-Ab-1/ GM-Tg-mg-IP2509-Ab-2 | Anti-Mouse GAGE1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2509-Ab-1/ GM-Tg-cynog-IP2509-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GAGE1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2509-Ab-1/ GM-Tg-felg-IP2509-Ab-2 | Anti-Feline GAGE1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2509-Ab-1/ GM-Tg-cang-IP2509-Ab-2 | Anti-Canine GAGE1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2509-Ab-1/ GM-Tg-bovg-IP2509-Ab-2 | Anti-Bovine GAGE1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2509-Ab-1/ GM-Tg-equg-IP2509-Ab-2 | Anti-Equine GAGE1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2509-Ab-1/ GM-Tg-hg-IP2509-Ab-2; GM-Tg-rg-IP2509-Ab-1/ GM-Tg-rg-IP2509-Ab-2; GM-Tg-mg-IP2509-Ab-1/ GM-Tg-mg-IP2509-Ab-2; GM-Tg-cynog-IP2509-Ab-1/ GM-Tg-cynog-IP2509-Ab-2; GM-Tg-felg-IP2509-Ab-1/ GM-Tg-felg-IP2509-Ab-2; GM-Tg-cang-IP2509-Ab-1/ GM-Tg-cang-IP2509-Ab-2; GM-Tg-bovg-IP2509-Ab-1/ GM-Tg-bovg-IP2509-Ab-2; GM-Tg-equg-IP2509-Ab-1/ GM-Tg-equg-IP2509-Ab-2 |
| Products Name | Anti-GAGE1 monoclonal antibody |
| Format | mab |
| Target Name | GAGE1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GAGE1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2509-Ag-1 | Recombinant multi-species GAGE1/ CT4.1/ CT4.4 protein |
Target information
| Target ID | GM-IP2509 |
| Target Name | GAGE1 |
| Gene ID | 2543 |
| Gene Symbol and Synonyms | CT4.1,CT4.4,GAGE-1,GAGE-4,GAGE1,GAGE4 |
| Uniprot Accession | P0DTW1 |
| Uniprot Entry Name | GAGE1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000205777 |
| Target Classification | N/A |
The target: GAGE1, gene name: GAGE1, also named as CT4.1, CT4.4, GAGE-1, GAGE-4, GAGE4. This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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