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Anti-GNB4 monoclonal antibody
Pre-made anti-GNB4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GNB4/GNB4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2527-Ab-1/ GM-Tg-hg-IP2527-Ab-2 | Anti-Human GNB4 monoclonal antibody | Human |
| GM-Tg-rg-IP2527-Ab-1/ GM-Tg-rg-IP2527-Ab-2 | Anti-Rat GNB4 monoclonal antibody | Rat |
| GM-Tg-mg-IP2527-Ab-1/ GM-Tg-mg-IP2527-Ab-2 | Anti-Mouse GNB4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2527-Ab-1/ GM-Tg-cynog-IP2527-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GNB4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2527-Ab-1/ GM-Tg-felg-IP2527-Ab-2 | Anti-Feline GNB4 monoclonal antibody | Feline |
| GM-Tg-cang-IP2527-Ab-1/ GM-Tg-cang-IP2527-Ab-2 | Anti-Canine GNB4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2527-Ab-1/ GM-Tg-bovg-IP2527-Ab-2 | Anti-Bovine GNB4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2527-Ab-1/ GM-Tg-equg-IP2527-Ab-2 | Anti-Equine GNB4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2527-Ab-1/ GM-Tg-hg-IP2527-Ab-2; GM-Tg-rg-IP2527-Ab-1/ GM-Tg-rg-IP2527-Ab-2; GM-Tg-mg-IP2527-Ab-1/ GM-Tg-mg-IP2527-Ab-2; GM-Tg-cynog-IP2527-Ab-1/ GM-Tg-cynog-IP2527-Ab-2; GM-Tg-felg-IP2527-Ab-1/ GM-Tg-felg-IP2527-Ab-2; GM-Tg-cang-IP2527-Ab-1/ GM-Tg-cang-IP2527-Ab-2; GM-Tg-bovg-IP2527-Ab-1/ GM-Tg-bovg-IP2527-Ab-2; GM-Tg-equg-IP2527-Ab-1/ GM-Tg-equg-IP2527-Ab-2 |
| Products Name | Anti-GNB4 monoclonal antibody |
| Format | mab |
| Target Name | GNB4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GNB4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2527-Ag-1 | Recombinant multi-species GBB4/ GNB4/ CMTD1F protein |
Target information
| Target ID | GM-IP2527 |
| Target Name | GNB4 |
| Gene ID | 59345,14696,294962,709489,488087,101091855,525962,100058274 |
| Gene Symbol and Synonyms | 6720453A21Rik,CMTD1F,G(beta)4,GNB4,HG2B |
| Uniprot Accession | Q9HAV0,O35353 |
| Uniprot Entry Name | GBB4_HUMAN,GBB4_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000114450 |
| Target Classification | N/A |
The target: GNB4, gene name: GNB4, also named as CMTD1F. Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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