- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-HOXC5 monoclonal antibody
Pre-made anti-HOXC5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HOXC5/HOXC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2539-Ab-1/ GM-Tg-hg-IP2539-Ab-2 | Anti-Human HOXC5 monoclonal antibody | Human |
| GM-Tg-rg-IP2539-Ab-1/ GM-Tg-rg-IP2539-Ab-2 | Anti-Rat HOXC5 monoclonal antibody | Rat |
| GM-Tg-mg-IP2539-Ab-1/ GM-Tg-mg-IP2539-Ab-2 | Anti-Mouse HOXC5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2539-Ab-1/ GM-Tg-cynog-IP2539-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HOXC5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2539-Ab-1/ GM-Tg-felg-IP2539-Ab-2 | Anti-Feline HOXC5 monoclonal antibody | Feline |
| GM-Tg-cang-IP2539-Ab-1/ GM-Tg-cang-IP2539-Ab-2 | Anti-Canine HOXC5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2539-Ab-1/ GM-Tg-bovg-IP2539-Ab-2 | Anti-Bovine HOXC5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2539-Ab-1/ GM-Tg-equg-IP2539-Ab-2 | Anti-Equine HOXC5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2539-Ab-1/ GM-Tg-hg-IP2539-Ab-2; GM-Tg-rg-IP2539-Ab-1/ GM-Tg-rg-IP2539-Ab-2; GM-Tg-mg-IP2539-Ab-1/ GM-Tg-mg-IP2539-Ab-2; GM-Tg-cynog-IP2539-Ab-1/ GM-Tg-cynog-IP2539-Ab-2; GM-Tg-felg-IP2539-Ab-1/ GM-Tg-felg-IP2539-Ab-2; GM-Tg-cang-IP2539-Ab-1/ GM-Tg-cang-IP2539-Ab-2; GM-Tg-bovg-IP2539-Ab-1/ GM-Tg-bovg-IP2539-Ab-2; GM-Tg-equg-IP2539-Ab-1/ GM-Tg-equg-IP2539-Ab-2 |
| Products Name | Anti-HOXC5 monoclonal antibody |
| Format | mab |
| Target Name | HOXC5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HOXC5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2539-Ag-1 | Recombinant multi-species HXC5/ HOXC5/ CP11 protein |
Target information
| Target ID | GM-IP2539 |
| Target Name | HOXC5 |
| Gene ID | 3222,15424,315341,107000877,102152615,101090952,100140629,100064385 |
| Gene Symbol and Synonyms | CP11,Hox-3.4,Hox-6.2,HOX3,HOX3D,HOXC5 |
| Uniprot Accession | Q00444 |
| Uniprot Entry Name | HXC5_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000172789 |
| Target Classification | N/A |
The target: HOXC5, gene name: HOXC5, also named as CP11, HOX3, HOX3D. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
