Anti-HYI monoclonal antibody

Pre-made anti-HYI monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to HYI/HYI products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2545-Ab-1/ GM-Tg-hg-IP2545-Ab-2Anti-Human HYI monoclonal antibodyHuman
GM-Tg-rg-IP2545-Ab-1/ GM-Tg-rg-IP2545-Ab-2Anti-Rat HYI monoclonal antibodyRat
GM-Tg-mg-IP2545-Ab-1/ GM-Tg-mg-IP2545-Ab-2Anti-Mouse HYI monoclonal antibodyMouse
GM-Tg-cynog-IP2545-Ab-1/ GM-Tg-cynog-IP2545-Ab-2Anti-Cynomolgus/ Rhesus macaque HYI monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2545-Ab-1/ GM-Tg-felg-IP2545-Ab-2Anti-Feline HYI monoclonal antibodyFeline
GM-Tg-cang-IP2545-Ab-1/ GM-Tg-cang-IP2545-Ab-2Anti-Canine HYI monoclonal antibodyCanine
GM-Tg-bovg-IP2545-Ab-1/ GM-Tg-bovg-IP2545-Ab-2Anti-Bovine HYI monoclonal antibodyBovine
GM-Tg-equg-IP2545-Ab-1/ GM-Tg-equg-IP2545-Ab-2Anti-Equine HYI monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2545-Ab-1/ GM-Tg-hg-IP2545-Ab-2; GM-Tg-rg-IP2545-Ab-1/ GM-Tg-rg-IP2545-Ab-2;
GM-Tg-mg-IP2545-Ab-1/ GM-Tg-mg-IP2545-Ab-2; GM-Tg-cynog-IP2545-Ab-1/ GM-Tg-cynog-IP2545-Ab-2;
GM-Tg-felg-IP2545-Ab-1/ GM-Tg-felg-IP2545-Ab-2; GM-Tg-cang-IP2545-Ab-1/ GM-Tg-cang-IP2545-Ab-2;
GM-Tg-bovg-IP2545-Ab-1/ GM-Tg-bovg-IP2545-Ab-2; GM-Tg-equg-IP2545-Ab-1/ GM-Tg-equg-IP2545-Ab-2
Products NameAnti-HYI monoclonal antibody
Formatmab
Target NameHYI
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-HYI monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2545-Ag-1Recombinant multi-species HYI/ HT036 protein


    Target information

    Target IDGM-IP2545
    Target NameHYI
    Gene ID81888,500536,700926,482531,101098729,515954,100066491
    Gene Symbol and SynonymsHT036,HYI,RGD1561416
    Uniprot AccessionQ5T013
    Uniprot Entry NameHYI_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178922
    Target ClassificationN/A

    The target: HYI, gene name: HYI, also named as HT036. This gene encodes a putative hydroxypyruvate isomerase, which likely catalyzes the conversion of hydroxypyruvate to 2-hydroxy-3-oxopropanoate, and may be involved in carbohydrate transport and metabolism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.