Anti-JCAD monoclonal antibody

Pre-made anti-JCAD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to JCAD/JCAD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2552-Ab-1/ GM-Tg-hg-IP2552-Ab-2Anti-Human JCAD monoclonal antibodyHuman
GM-Tg-rg-IP2552-Ab-1/ GM-Tg-rg-IP2552-Ab-2Anti-Rat JCAD monoclonal antibodyRat
GM-Tg-mg-IP2552-Ab-1/ GM-Tg-mg-IP2552-Ab-2Anti-Mouse JCAD monoclonal antibodyMouse
GM-Tg-cynog-IP2552-Ab-1/ GM-Tg-cynog-IP2552-Ab-2Anti-Cynomolgus/ Rhesus macaque JCAD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2552-Ab-1/ GM-Tg-felg-IP2552-Ab-2Anti-Feline JCAD monoclonal antibodyFeline
GM-Tg-cang-IP2552-Ab-1/ GM-Tg-cang-IP2552-Ab-2Anti-Canine JCAD monoclonal antibodyCanine
GM-Tg-bovg-IP2552-Ab-1/ GM-Tg-bovg-IP2552-Ab-2Anti-Bovine JCAD monoclonal antibodyBovine
GM-Tg-equg-IP2552-Ab-1/ GM-Tg-equg-IP2552-Ab-2Anti-Equine JCAD monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2552-Ab-1/ GM-Tg-hg-IP2552-Ab-2; GM-Tg-rg-IP2552-Ab-1/ GM-Tg-rg-IP2552-Ab-2;
GM-Tg-mg-IP2552-Ab-1/ GM-Tg-mg-IP2552-Ab-2; GM-Tg-cynog-IP2552-Ab-1/ GM-Tg-cynog-IP2552-Ab-2;
GM-Tg-felg-IP2552-Ab-1/ GM-Tg-felg-IP2552-Ab-2; GM-Tg-cang-IP2552-Ab-1/ GM-Tg-cang-IP2552-Ab-2;
GM-Tg-bovg-IP2552-Ab-1/ GM-Tg-bovg-IP2552-Ab-2; GM-Tg-equg-IP2552-Ab-1/ GM-Tg-equg-IP2552-Ab-2
Products NameAnti-JCAD monoclonal antibody
Formatmab
Target NameJCAD
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-JCAD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2552-Ag-1Recombinant multi-species JCAD/ KIAA1462 protein


    Target information

    Target IDGM-IP2552
    Target NameJCAD
    Gene ID57608,240185,498764,694100,477964,101091121,784675,100063438
    Gene Symbol and Synonyms1110056P05Rik,9430020K01Rik,Gm328,JCAD,KIAA1462,mKIAA1462,RGD1562037
    Uniprot AccessionQ9P266,A2VE02
    Uniprot Entry NameJCAD_HUMAN,JCAD_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165757
    Target ClassificationN/A

    The target: JCAD, gene name: JCAD, also named as KIAA1462. This gene encodes an endothelial cell-to-cell junction protein. Naturally occurring mutations in this gene are associated with coronary artery disease, late onset alzheimer disease, and emphysema distribution. [provided by RefSeq, Mar 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.