Anti-JMJD4 monoclonal antibody

Pre-made anti-JMJD4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to JMJD4/JMJD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2553-Ab-1/ GM-Tg-hg-IP2553-Ab-2Anti-Human JMJD4 monoclonal antibodyHuman
GM-Tg-rg-IP2553-Ab-1/ GM-Tg-rg-IP2553-Ab-2Anti-Rat JMJD4 monoclonal antibodyRat
GM-Tg-mg-IP2553-Ab-1/ GM-Tg-mg-IP2553-Ab-2Anti-Mouse JMJD4 monoclonal antibodyMouse
GM-Tg-cynog-IP2553-Ab-1/ GM-Tg-cynog-IP2553-Ab-2Anti-Cynomolgus/ Rhesus macaque JMJD4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2553-Ab-1/ GM-Tg-felg-IP2553-Ab-2Anti-Feline JMJD4 monoclonal antibodyFeline
GM-Tg-cang-IP2553-Ab-1/ GM-Tg-cang-IP2553-Ab-2Anti-Canine JMJD4 monoclonal antibodyCanine
GM-Tg-bovg-IP2553-Ab-1/ GM-Tg-bovg-IP2553-Ab-2Anti-Bovine JMJD4 monoclonal antibodyBovine
GM-Tg-equg-IP2553-Ab-1/ GM-Tg-equg-IP2553-Ab-2Anti-Equine JMJD4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2553-Ab-1/ GM-Tg-hg-IP2553-Ab-2; GM-Tg-rg-IP2553-Ab-1/ GM-Tg-rg-IP2553-Ab-2;
GM-Tg-mg-IP2553-Ab-1/ GM-Tg-mg-IP2553-Ab-2; GM-Tg-cynog-IP2553-Ab-1/ GM-Tg-cynog-IP2553-Ab-2;
GM-Tg-felg-IP2553-Ab-1/ GM-Tg-felg-IP2553-Ab-2; GM-Tg-cang-IP2553-Ab-1/ GM-Tg-cang-IP2553-Ab-2;
GM-Tg-bovg-IP2553-Ab-1/ GM-Tg-bovg-IP2553-Ab-2; GM-Tg-equg-IP2553-Ab-1/ GM-Tg-equg-IP2553-Ab-2
Products NameAnti-JMJD4 monoclonal antibody
Formatmab
Target NameJMJD4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-JMJD4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2553-Ag-1Recombinant multi-species JMJD4 protein
    ORF Viral VectorpGMLPm005198mouse Jmjd4 Lentivirus plasmid
    ORF Viral VectorvGMLPm005198mouse Jmjd4 Lentivirus particle


    Target information

    Target IDGM-IP2553
    Target NameJMJD4
    Gene ID65094,194952,287359,696580,475182,101100782,506151,100061047
    Gene Symbol and Synonyms6430559I23,JMJD4,RGD1307186
    Uniprot AccessionQ9H9V9
    Uniprot Entry NameJMJD4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000081692
    Target ClassificationN/A

    The target: JMJD4, gene name: JMJD4, also named as . Enables 2-oxoglutarate-dependent dioxygenase activity. Involved in positive regulation of translational termination and protein hydroxylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.