Anti-KDF1 monoclonal antibody

Pre-made anti-KDF1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to KDF1/KDF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2555-Ab-1/ GM-Tg-hg-IP2555-Ab-2Anti-Human KDF1 monoclonal antibodyHuman
GM-Tg-rg-IP2555-Ab-1/ GM-Tg-rg-IP2555-Ab-2Anti-Rat KDF1 monoclonal antibodyRat
GM-Tg-mg-IP2555-Ab-1/ GM-Tg-mg-IP2555-Ab-2Anti-Mouse KDF1 monoclonal antibodyMouse
GM-Tg-cynog-IP2555-Ab-1/ GM-Tg-cynog-IP2555-Ab-2Anti-Cynomolgus/ Rhesus macaque KDF1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2555-Ab-1/ GM-Tg-felg-IP2555-Ab-2Anti-Feline KDF1 monoclonal antibodyFeline
GM-Tg-cang-IP2555-Ab-1/ GM-Tg-cang-IP2555-Ab-2Anti-Canine KDF1 monoclonal antibodyCanine
GM-Tg-bovg-IP2555-Ab-1/ GM-Tg-bovg-IP2555-Ab-2Anti-Bovine KDF1 monoclonal antibodyBovine
GM-Tg-equg-IP2555-Ab-1/ GM-Tg-equg-IP2555-Ab-2Anti-Equine KDF1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2555-Ab-1/ GM-Tg-hg-IP2555-Ab-2; GM-Tg-rg-IP2555-Ab-1/ GM-Tg-rg-IP2555-Ab-2;
GM-Tg-mg-IP2555-Ab-1/ GM-Tg-mg-IP2555-Ab-2; GM-Tg-cynog-IP2555-Ab-1/ GM-Tg-cynog-IP2555-Ab-2;
GM-Tg-felg-IP2555-Ab-1/ GM-Tg-felg-IP2555-Ab-2; GM-Tg-cang-IP2555-Ab-1/ GM-Tg-cang-IP2555-Ab-2;
GM-Tg-bovg-IP2555-Ab-1/ GM-Tg-bovg-IP2555-Ab-2; GM-Tg-equg-IP2555-Ab-1/ GM-Tg-equg-IP2555-Ab-2
Products NameAnti-KDF1 monoclonal antibody
Formatmab
Target NameKDF1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-KDF1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2555-Ag-1Recombinant multi-species KDF1/ C1orf172/ ECTD12 protein


    Target information

    Target IDGM-IP2555
    Target NameKDF1
    Gene ID126695,69073,313018,715312,612121,101088257,540019,100057007
    Gene Symbol and Synonyms1810019J16Rik,C1orf172,C2H1orf172,CC1H1orf172,ECTD12,KDF1,RGD1303271
    Uniprot AccessionQ8NAX2,Q6AY88
    Uniprot Entry NameKDF1_HUMAN,KDF1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000175707
    Target ClassificationN/A

    The target: KDF1, gene name: KDF1, also named as C1orf172, ECTD12. Predicted to be involved in several processes, including positive regulation of epidermal cell differentiation; regulation of epidermal cell division; and skin development. Predicted to act upstream of or within keratinocyte development and negative regulation of keratinocyte proliferation. Located in cell junction; mitotic spindle; and nucleoplasm. Implicated in ectodermal dysplasia 12. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.