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Anti-KIF21B monoclonal antibody
Pre-made anti-KIF21B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to KIF21B/KIF21B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2562-Ab-1/ GM-Tg-hg-IP2562-Ab-2 | Anti-Human KIF21B monoclonal antibody | Human |
| GM-Tg-rg-IP2562-Ab-1/ GM-Tg-rg-IP2562-Ab-2 | Anti-Rat KIF21B monoclonal antibody | Rat |
| GM-Tg-mg-IP2562-Ab-1/ GM-Tg-mg-IP2562-Ab-2 | Anti-Mouse KIF21B monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2562-Ab-1/ GM-Tg-cynog-IP2562-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KIF21B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2562-Ab-1/ GM-Tg-felg-IP2562-Ab-2 | Anti-Feline KIF21B monoclonal antibody | Feline |
| GM-Tg-cang-IP2562-Ab-1/ GM-Tg-cang-IP2562-Ab-2 | Anti-Canine KIF21B monoclonal antibody | Canine |
| GM-Tg-bovg-IP2562-Ab-1/ GM-Tg-bovg-IP2562-Ab-2 | Anti-Bovine KIF21B monoclonal antibody | Bovine |
| GM-Tg-equg-IP2562-Ab-1/ GM-Tg-equg-IP2562-Ab-2 | Anti-Equine KIF21B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2562-Ab-1/ GM-Tg-hg-IP2562-Ab-2; GM-Tg-rg-IP2562-Ab-1/ GM-Tg-rg-IP2562-Ab-2; GM-Tg-mg-IP2562-Ab-1/ GM-Tg-mg-IP2562-Ab-2; GM-Tg-cynog-IP2562-Ab-1/ GM-Tg-cynog-IP2562-Ab-2; GM-Tg-felg-IP2562-Ab-1/ GM-Tg-felg-IP2562-Ab-2; GM-Tg-cang-IP2562-Ab-1/ GM-Tg-cang-IP2562-Ab-2; GM-Tg-bovg-IP2562-Ab-1/ GM-Tg-bovg-IP2562-Ab-2; GM-Tg-equg-IP2562-Ab-1/ GM-Tg-equg-IP2562-Ab-2 |
| Products Name | Anti-KIF21B monoclonal antibody |
| Format | mab |
| Target Name | KIF21B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-KIF21B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2562-Ag-1 | Recombinant multi-species KI21B/ KIF21B protein |
Target information
| Target ID | GM-IP2562 |
| Target Name | KIF21B |
| Gene ID | 23046,16565,289397,710792,490245,101098602,100337196,100063175 |
| Gene Symbol and Synonyms | 2610511N21Rik,KIF21B,mKIAA0449 |
| Uniprot Accession | O75037,F1M5N7 |
| Uniprot Entry Name | KI21B_HUMAN,KI21B_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000116852 |
| Target Classification | N/A |
The target: KIF21B, gene name: KIF21B, also named as . This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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