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Anti-KRT75 monoclonal antibody
Pre-made anti-KRT75 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to KRT75/KRT75 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2569-Ab-1/ GM-Tg-hg-IP2569-Ab-2 | Anti-Human KRT75 monoclonal antibody | Human |
| GM-Tg-rg-IP2569-Ab-1/ GM-Tg-rg-IP2569-Ab-2 | Anti-Rat KRT75 monoclonal antibody | Rat |
| GM-Tg-mg-IP2569-Ab-1/ GM-Tg-mg-IP2569-Ab-2 | Anti-Mouse KRT75 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2569-Ab-1/ GM-Tg-cynog-IP2569-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KRT75 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2569-Ab-1/ GM-Tg-felg-IP2569-Ab-2 | Anti-Feline KRT75 monoclonal antibody | Feline |
| GM-Tg-cang-IP2569-Ab-1/ GM-Tg-cang-IP2569-Ab-2 | Anti-Canine KRT75 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2569-Ab-1/ GM-Tg-bovg-IP2569-Ab-2 | Anti-Bovine KRT75 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2569-Ab-1/ GM-Tg-equg-IP2569-Ab-2 | Anti-Equine KRT75 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2569-Ab-1/ GM-Tg-hg-IP2569-Ab-2; GM-Tg-rg-IP2569-Ab-1/ GM-Tg-rg-IP2569-Ab-2; GM-Tg-mg-IP2569-Ab-1/ GM-Tg-mg-IP2569-Ab-2; GM-Tg-cynog-IP2569-Ab-1/ GM-Tg-cynog-IP2569-Ab-2; GM-Tg-felg-IP2569-Ab-1/ GM-Tg-felg-IP2569-Ab-2; GM-Tg-cang-IP2569-Ab-1/ GM-Tg-cang-IP2569-Ab-2; GM-Tg-bovg-IP2569-Ab-1/ GM-Tg-bovg-IP2569-Ab-2; GM-Tg-equg-IP2569-Ab-1/ GM-Tg-equg-IP2569-Ab-2 |
| Products Name | Anti-KRT75 monoclonal antibody |
| Format | mab |
| Target Name | KRT75 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-KRT75 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2569-Ag-1 | Recombinant multi-species K2C75/ KRT75/ K6HF protein |
Target information
| Target ID | GM-IP2569 |
| Target Name | KRT75 |
| Gene ID | 9119,300247,699682,539683 |
| Gene Symbol and Synonyms | CK-75,hK6hf,K6HF,K75,KB18,KRT75,PFB |
| Uniprot Accession | O95678,Q6IG05,Q08D91 |
| Uniprot Entry Name | K2C75_HUMAN,K2C75_RAT,K2C75_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000170454 |
| Target Classification | N/A |
The target: KRT75, gene name: KRT75, also named as K6HF, KB18, PFB. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq, Oct 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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