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Anti-LGALS8 monoclonal antibody
Pre-made anti-LGALS8 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LGALS8/LGALS8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2573-Ab-1/ GM-Tg-hg-IP2573-Ab-2 | Anti-Human LGALS8 monoclonal antibody | Human |
| GM-Tg-rg-IP2573-Ab-1/ GM-Tg-rg-IP2573-Ab-2 | Anti-Rat LGALS8 monoclonal antibody | Rat |
| GM-Tg-mg-IP2573-Ab-1/ GM-Tg-mg-IP2573-Ab-2 | Anti-Mouse LGALS8 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2573-Ab-1/ GM-Tg-cynog-IP2573-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LGALS8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2573-Ab-1/ GM-Tg-felg-IP2573-Ab-2 | Anti-Feline LGALS8 monoclonal antibody | Feline |
| GM-Tg-cang-IP2573-Ab-1/ GM-Tg-cang-IP2573-Ab-2 | Anti-Canine LGALS8 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2573-Ab-1/ GM-Tg-bovg-IP2573-Ab-2 | Anti-Bovine LGALS8 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2573-Ab-1/ GM-Tg-equg-IP2573-Ab-2 | Anti-Equine LGALS8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2573-Ab-1/ GM-Tg-hg-IP2573-Ab-2; GM-Tg-rg-IP2573-Ab-1/ GM-Tg-rg-IP2573-Ab-2; GM-Tg-mg-IP2573-Ab-1/ GM-Tg-mg-IP2573-Ab-2; GM-Tg-cynog-IP2573-Ab-1/ GM-Tg-cynog-IP2573-Ab-2; GM-Tg-felg-IP2573-Ab-1/ GM-Tg-felg-IP2573-Ab-2; GM-Tg-cang-IP2573-Ab-1/ GM-Tg-cang-IP2573-Ab-2; GM-Tg-bovg-IP2573-Ab-1/ GM-Tg-bovg-IP2573-Ab-2; GM-Tg-equg-IP2573-Ab-1/ GM-Tg-equg-IP2573-Ab-2 |
| Products Name | Anti-LGALS8 monoclonal antibody |
| Format | mab |
| Target Name | LGALS8 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LGALS8 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2573-Ag-1 | Recombinant multi-species LEG8/ LGALS8/ Gal-8 protein |
Target information
| Target ID | GM-IP2573 |
| Target Name | LGALS8 |
| Gene ID | 3964,56048,116641,710375,479193,101101669,506977,100050491 |
| Gene Symbol and Synonyms | 1200015E08Rik,D13Ertd524e,Gal-8,galectin-8,Lgals-8,LGALS8,PCTA-1,PCTA1,Po66-CBP |
| Uniprot Accession | O00214,Q62665 |
| Uniprot Entry Name | LEG8_HUMAN,LEG8_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000116977 |
| Target Classification | N/A |
The target: LGALS8, gene name: LGALS8, also named as Gal-8, PCTA-1, PCTA1, Po66-CBP. This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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