Anti-LHX6 monoclonal antibody
Pre-made anti-LHX6 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LHX6/LHX6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP2574-Ab-1/ GM-Tg-hg-IP2574-Ab-2 | Anti-Human LHX6 monoclonal antibody | Human |
GM-Tg-rg-IP2574-Ab-1/ GM-Tg-rg-IP2574-Ab-2 | Anti-Rat LHX6 monoclonal antibody | Rat |
GM-Tg-mg-IP2574-Ab-1/ GM-Tg-mg-IP2574-Ab-2 | Anti-Mouse LHX6 monoclonal antibody | Mouse |
GM-Tg-cynog-IP2574-Ab-1/ GM-Tg-cynog-IP2574-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LHX6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP2574-Ab-1/ GM-Tg-felg-IP2574-Ab-2 | Anti-Feline LHX6 monoclonal antibody | Feline |
GM-Tg-cang-IP2574-Ab-1/ GM-Tg-cang-IP2574-Ab-2 | Anti-Canine LHX6 monoclonal antibody | Canine |
GM-Tg-bovg-IP2574-Ab-1/ GM-Tg-bovg-IP2574-Ab-2 | Anti-Bovine LHX6 monoclonal antibody | Bovine |
GM-Tg-equg-IP2574-Ab-1/ GM-Tg-equg-IP2574-Ab-2 | Anti-Equine LHX6 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP2574-Ab-1/ GM-Tg-hg-IP2574-Ab-2; GM-Tg-rg-IP2574-Ab-1/ GM-Tg-rg-IP2574-Ab-2; GM-Tg-mg-IP2574-Ab-1/ GM-Tg-mg-IP2574-Ab-2; GM-Tg-cynog-IP2574-Ab-1/ GM-Tg-cynog-IP2574-Ab-2; GM-Tg-felg-IP2574-Ab-1/ GM-Tg-felg-IP2574-Ab-2; GM-Tg-cang-IP2574-Ab-1/ GM-Tg-cang-IP2574-Ab-2; GM-Tg-bovg-IP2574-Ab-1/ GM-Tg-bovg-IP2574-Ab-2; GM-Tg-equg-IP2574-Ab-1/ GM-Tg-equg-IP2574-Ab-2 |
Products Name | Anti-LHX6 monoclonal antibody |
Format | mab |
Target Name | LHX6 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-LHX6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP2574-Ag-1 | Recombinant multi-species LHX6/ LHX6.1 protein |
Target information
Target ID | GM-IP2574 |
Target Name | LHX6 |
Gene ID | 26468,16874,311901,698587,491354,101091662,541261,100147107 |
Gene Symbol and Synonyms | hLHX6,LHX6,LHX6.1 |
Uniprot Accession | Q9UPM6 |
Uniprot Entry Name | LHX6_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000106852 |
Target Classification | N/A |
The target: LHX6, gene name: LHX6, also named as LHX6.1. This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein has tandem LIM domains as well as a DNA-binding homeodomain. The protein functions as a transcription factor involved in embryogenesis and head development and is highly expressed in neural crest derived mesenchyme cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.