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Anti-LPIN1 monoclonal antibody
Pre-made anti-LPIN1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LPIN1/LPIN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2578-Ab-1/ GM-Tg-hg-IP2578-Ab-2 | Anti-Human LPIN1 monoclonal antibody | Human |
| GM-Tg-rg-IP2578-Ab-1/ GM-Tg-rg-IP2578-Ab-2 | Anti-Rat LPIN1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2578-Ab-1/ GM-Tg-mg-IP2578-Ab-2 | Anti-Mouse LPIN1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2578-Ab-1/ GM-Tg-cynog-IP2578-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LPIN1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2578-Ab-1/ GM-Tg-felg-IP2578-Ab-2 | Anti-Feline LPIN1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2578-Ab-1/ GM-Tg-cang-IP2578-Ab-2 | Anti-Canine LPIN1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2578-Ab-1/ GM-Tg-bovg-IP2578-Ab-2 | Anti-Bovine LPIN1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2578-Ab-1/ GM-Tg-equg-IP2578-Ab-2 | Anti-Equine LPIN1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2578-Ab-1/ GM-Tg-hg-IP2578-Ab-2; GM-Tg-rg-IP2578-Ab-1/ GM-Tg-rg-IP2578-Ab-2; GM-Tg-mg-IP2578-Ab-1/ GM-Tg-mg-IP2578-Ab-2; GM-Tg-cynog-IP2578-Ab-1/ GM-Tg-cynog-IP2578-Ab-2; GM-Tg-felg-IP2578-Ab-1/ GM-Tg-felg-IP2578-Ab-2; GM-Tg-cang-IP2578-Ab-1/ GM-Tg-cang-IP2578-Ab-2; GM-Tg-bovg-IP2578-Ab-1/ GM-Tg-bovg-IP2578-Ab-2; GM-Tg-equg-IP2578-Ab-1/ GM-Tg-equg-IP2578-Ab-2 |
| Products Name | Anti-LPIN1 monoclonal antibody |
| Format | mab |
| Target Name | LPIN1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LPIN1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2578-Ag-1 | Recombinant multi-species LPIN1/ PAP1 protein |
Target information
| Target ID | GM-IP2578 |
| Target Name | LPIN1 |
| Gene ID | 23175,14245,313977,697682,475670,101085623,537224,100072273 |
| Gene Symbol and Synonyms | fld,Lipin1,LPIN1,PAP1 |
| Uniprot Accession | Q14693 |
| Uniprot Entry Name | LPIN1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000134324 |
| Target Classification | N/A |
The target: LPIN1, gene name: LPIN1, also named as PAP1. This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
