Anti-METTL15 monoclonal antibody

Pre-made anti-METTL15 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to METTL15/METTL15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2595-Ab-1/ GM-Tg-hg-IP2595-Ab-2Anti-Human METTL15 monoclonal antibodyHuman
GM-Tg-rg-IP2595-Ab-1/ GM-Tg-rg-IP2595-Ab-2Anti-Rat METTL15 monoclonal antibodyRat
GM-Tg-mg-IP2595-Ab-1/ GM-Tg-mg-IP2595-Ab-2Anti-Mouse METTL15 monoclonal antibodyMouse
GM-Tg-cynog-IP2595-Ab-1/ GM-Tg-cynog-IP2595-Ab-2Anti-Cynomolgus/ Rhesus macaque METTL15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2595-Ab-1/ GM-Tg-felg-IP2595-Ab-2Anti-Feline METTL15 monoclonal antibodyFeline
GM-Tg-cang-IP2595-Ab-1/ GM-Tg-cang-IP2595-Ab-2Anti-Canine METTL15 monoclonal antibodyCanine
GM-Tg-bovg-IP2595-Ab-1/ GM-Tg-bovg-IP2595-Ab-2Anti-Bovine METTL15 monoclonal antibodyBovine
GM-Tg-equg-IP2595-Ab-1/ GM-Tg-equg-IP2595-Ab-2Anti-Equine METTL15 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2595-Ab-1/ GM-Tg-hg-IP2595-Ab-2; GM-Tg-rg-IP2595-Ab-1/ GM-Tg-rg-IP2595-Ab-2;
GM-Tg-mg-IP2595-Ab-1/ GM-Tg-mg-IP2595-Ab-2; GM-Tg-cynog-IP2595-Ab-1/ GM-Tg-cynog-IP2595-Ab-2;
GM-Tg-felg-IP2595-Ab-1/ GM-Tg-felg-IP2595-Ab-2; GM-Tg-cang-IP2595-Ab-1/ GM-Tg-cang-IP2595-Ab-2;
GM-Tg-bovg-IP2595-Ab-1/ GM-Tg-bovg-IP2595-Ab-2; GM-Tg-equg-IP2595-Ab-1/ GM-Tg-equg-IP2595-Ab-2
Products NameAnti-METTL15 monoclonal antibody
Formatmab
Target NameMETTL15
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-METTL15 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2595-Ag-1Recombinant multi-species MET15/ METTL15/ METT5D1 protein


    Target information

    Target IDGM-IP2595
    Target NameMETTL15
    Gene ID196074,76894,295985,698208,476897,101083204,533987,100072431
    Gene Symbol and Synonyms0610027B03Rik,METT5D1,METTL15,RGD1304978
    Uniprot AccessionA6NJ78,A0JN95
    Uniprot Entry NameMET15_HUMAN,MET15_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169519
    Target ClassificationN/A

    The target: METTL15, gene name: METTL15, also named as METT5D1. Predicted to enable rRNA (cytosine-N4-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.