Anti-MRNIP monoclonal antibody

Pre-made anti-MRNIP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MRNIP/MRNIP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2605-Ab-1/ GM-Tg-hg-IP2605-Ab-2Anti-Human MRNIP monoclonal antibodyHuman
GM-Tg-rg-IP2605-Ab-1/ GM-Tg-rg-IP2605-Ab-2Anti-Rat MRNIP monoclonal antibodyRat
GM-Tg-mg-IP2605-Ab-1/ GM-Tg-mg-IP2605-Ab-2Anti-Mouse MRNIP monoclonal antibodyMouse
GM-Tg-cynog-IP2605-Ab-1/ GM-Tg-cynog-IP2605-Ab-2Anti-Cynomolgus/ Rhesus macaque MRNIP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2605-Ab-1/ GM-Tg-felg-IP2605-Ab-2Anti-Feline MRNIP monoclonal antibodyFeline
GM-Tg-cang-IP2605-Ab-1/ GM-Tg-cang-IP2605-Ab-2Anti-Canine MRNIP monoclonal antibodyCanine
GM-Tg-bovg-IP2605-Ab-1/ GM-Tg-bovg-IP2605-Ab-2Anti-Bovine MRNIP monoclonal antibodyBovine
GM-Tg-equg-IP2605-Ab-1/ GM-Tg-equg-IP2605-Ab-2Anti-Equine MRNIP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2605-Ab-1/ GM-Tg-hg-IP2605-Ab-2; GM-Tg-rg-IP2605-Ab-1/ GM-Tg-rg-IP2605-Ab-2;
GM-Tg-mg-IP2605-Ab-1/ GM-Tg-mg-IP2605-Ab-2; GM-Tg-cynog-IP2605-Ab-1/ GM-Tg-cynog-IP2605-Ab-2;
GM-Tg-felg-IP2605-Ab-1/ GM-Tg-felg-IP2605-Ab-2; GM-Tg-cang-IP2605-Ab-1/ GM-Tg-cang-IP2605-Ab-2;
GM-Tg-bovg-IP2605-Ab-1/ GM-Tg-bovg-IP2605-Ab-2; GM-Tg-equg-IP2605-Ab-1/ GM-Tg-equg-IP2605-Ab-2
Products NameAnti-MRNIP monoclonal antibody
Formatmab
Target NameMRNIP
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MRNIP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2605-Ag-1Recombinant multi-species MRNIP/ C5orf45 protein


    Target information

    Target IDGM-IP2605
    Target NameMRNIP
    Gene ID51149,68067,497895,705595,607250,101095710,614757,100067209
    Gene Symbol and Synonyms2900016G09Rik,3010026O09Rik,C11H5orf45,C14H5orf45,C5orf45,C6H5orf45,C7H5orf45,CA1H5orf45,MRNIP,RGD1564036
    Uniprot AccessionQ6NTE8,Q3ZBG8
    Uniprot Entry NameMRNIP_HUMAN,MRNIP_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000161010
    Target ClassificationN/A

    The target: MRNIP, gene name: MRNIP, also named as C5orf45. Enables chromatin binding activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of double-strand break repair; and response to ionizing radiation. Located in nucleoplasm. Colocalizes with Mre11 complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.