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Anti-MTPN monoclonal antibody
Pre-made anti-MTPN monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MTPN/MTPN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2612-Ab-1/ GM-Tg-hg-IP2612-Ab-2 | Anti-Human MTPN monoclonal antibody | Human |
| GM-Tg-rg-IP2612-Ab-1/ GM-Tg-rg-IP2612-Ab-2 | Anti-Rat MTPN monoclonal antibody | Rat |
| GM-Tg-mg-IP2612-Ab-1/ GM-Tg-mg-IP2612-Ab-2 | Anti-Mouse MTPN monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2612-Ab-1/ GM-Tg-cynog-IP2612-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MTPN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2612-Ab-1/ GM-Tg-felg-IP2612-Ab-2 | Anti-Feline MTPN monoclonal antibody | Feline |
| GM-Tg-cang-IP2612-Ab-1/ GM-Tg-cang-IP2612-Ab-2 | Anti-Canine MTPN monoclonal antibody | Canine |
| GM-Tg-bovg-IP2612-Ab-1/ GM-Tg-bovg-IP2612-Ab-2 | Anti-Bovine MTPN monoclonal antibody | Bovine |
| GM-Tg-equg-IP2612-Ab-1/ GM-Tg-equg-IP2612-Ab-2 | Anti-Equine MTPN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2612-Ab-1/ GM-Tg-hg-IP2612-Ab-2; GM-Tg-rg-IP2612-Ab-1/ GM-Tg-rg-IP2612-Ab-2; GM-Tg-mg-IP2612-Ab-1/ GM-Tg-mg-IP2612-Ab-2; GM-Tg-cynog-IP2612-Ab-1/ GM-Tg-cynog-IP2612-Ab-2; GM-Tg-felg-IP2612-Ab-1/ GM-Tg-felg-IP2612-Ab-2; GM-Tg-cang-IP2612-Ab-1/ GM-Tg-cang-IP2612-Ab-2; GM-Tg-bovg-IP2612-Ab-1/ GM-Tg-bovg-IP2612-Ab-2; GM-Tg-equg-IP2612-Ab-1/ GM-Tg-equg-IP2612-Ab-2 |
| Products Name | Anti-MTPN monoclonal antibody |
| Format | mab |
| Target Name | MTPN |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MTPN monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2612-Ag-1 | Recombinant multi-species MTPN/ GCDP/ V-1 protein |
| ORF Viral Vector | pGMLP003390 | human MTPN Lentivirus plasmid |
| ORF Viral Vector | vGMLP003390 | human MTPN Lentivirus particle |
| ORF Viral Vector | pGMLPm002364 | mouse Mtpn Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002364 | mouse Mtpn Lentivirus particle |
Target information
| Target ID | GM-IP2612 |
| Target Name | MTPN |
| Gene ID | 136319,14489,79215,708941,403487,101097881,541099,100064934 |
| Gene Symbol and Synonyms | 5033418D15Rik,GCDP,MTPN,V-1,V1 |
| Uniprot Accession | P58546,P62775,Q863Z4,Q3T0F7 |
| Uniprot Entry Name | MTPN_HUMAN,MTPN_RAT,MTPN_CANLF,MTPN_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000105887 |
| Target Classification | N/A |
The target: MTPN, gene name: MTPN, also named as GCDP, V-1. The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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