- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-NUDCD3 monoclonal antibody
Pre-made anti-NUDCD3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NUDCD3/NUDCD3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2632-Ab-1/ GM-Tg-hg-IP2632-Ab-2 | Anti-Human NUDCD3 monoclonal antibody | Human |
| GM-Tg-rg-IP2632-Ab-1/ GM-Tg-rg-IP2632-Ab-2 | Anti-Rat NUDCD3 monoclonal antibody | Rat |
| GM-Tg-mg-IP2632-Ab-1/ GM-Tg-mg-IP2632-Ab-2 | Anti-Mouse NUDCD3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2632-Ab-1/ GM-Tg-cynog-IP2632-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NUDCD3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2632-Ab-1/ GM-Tg-felg-IP2632-Ab-2 | Anti-Feline NUDCD3 monoclonal antibody | Feline |
| GM-Tg-cang-IP2632-Ab-1/ GM-Tg-cang-IP2632-Ab-2 | Anti-Canine NUDCD3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2632-Ab-1/ GM-Tg-bovg-IP2632-Ab-2 | Anti-Bovine NUDCD3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2632-Ab-1/ GM-Tg-equg-IP2632-Ab-2 | Anti-Equine NUDCD3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2632-Ab-1/ GM-Tg-hg-IP2632-Ab-2; GM-Tg-rg-IP2632-Ab-1/ GM-Tg-rg-IP2632-Ab-2; GM-Tg-mg-IP2632-Ab-1/ GM-Tg-mg-IP2632-Ab-2; GM-Tg-cynog-IP2632-Ab-1/ GM-Tg-cynog-IP2632-Ab-2; GM-Tg-felg-IP2632-Ab-1/ GM-Tg-felg-IP2632-Ab-2; GM-Tg-cang-IP2632-Ab-1/ GM-Tg-cang-IP2632-Ab-2; GM-Tg-bovg-IP2632-Ab-1/ GM-Tg-bovg-IP2632-Ab-2; GM-Tg-equg-IP2632-Ab-1/ GM-Tg-equg-IP2632-Ab-2 |
| Products Name | Anti-NUDCD3 monoclonal antibody |
| Format | mab |
| Target Name | NUDCD3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NUDCD3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2632-Ag-1 | Recombinant multi-species NUDC3/ NUDCD3/ NudCL protein |
Target information
| Target ID | GM-IP2632 |
| Target Name | NUDCD3 |
| Gene ID | 23386,209586,100125378,699353,608096,111559463,533678,100065072 |
| Gene Symbol and Synonyms | mKIAA1068,NUDCD3,NudCL |
| Uniprot Accession | Q8IVD9 |
| Uniprot Entry Name | NUDC3_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000015676 |
| Target Classification | N/A |
The target: NUDCD3, gene name: NUDCD3, also named as NudCL. The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
