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Anti-PAK6 monoclonal antibody
Pre-made anti-PAK6 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PAK6/PAK6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2640-Ab-1/ GM-Tg-hg-IP2640-Ab-2 | Anti-Human PAK6 monoclonal antibody | Human |
| GM-Tg-rg-IP2640-Ab-1/ GM-Tg-rg-IP2640-Ab-2 | Anti-Rat PAK6 monoclonal antibody | Rat |
| GM-Tg-mg-IP2640-Ab-1/ GM-Tg-mg-IP2640-Ab-2 | Anti-Mouse PAK6 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2640-Ab-1/ GM-Tg-cynog-IP2640-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PAK6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2640-Ab-1/ GM-Tg-felg-IP2640-Ab-2 | Anti-Feline PAK6 monoclonal antibody | Feline |
| GM-Tg-cang-IP2640-Ab-1/ GM-Tg-cang-IP2640-Ab-2 | Anti-Canine PAK6 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2640-Ab-1/ GM-Tg-bovg-IP2640-Ab-2 | Anti-Bovine PAK6 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2640-Ab-1/ GM-Tg-equg-IP2640-Ab-2 | Anti-Equine PAK6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2640-Ab-1/ GM-Tg-hg-IP2640-Ab-2; GM-Tg-rg-IP2640-Ab-1/ GM-Tg-rg-IP2640-Ab-2; GM-Tg-mg-IP2640-Ab-1/ GM-Tg-mg-IP2640-Ab-2; GM-Tg-cynog-IP2640-Ab-1/ GM-Tg-cynog-IP2640-Ab-2; GM-Tg-felg-IP2640-Ab-1/ GM-Tg-felg-IP2640-Ab-2; GM-Tg-cang-IP2640-Ab-1/ GM-Tg-cang-IP2640-Ab-2; GM-Tg-bovg-IP2640-Ab-1/ GM-Tg-bovg-IP2640-Ab-2; GM-Tg-equg-IP2640-Ab-1/ GM-Tg-equg-IP2640-Ab-2 |
| Products Name | Anti-PAK6 monoclonal antibody |
| Format | mab |
| Target Name | PAK6 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PAK6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2640-Ag-1 | Recombinant multi-species PAK6/ PAK5 protein |
| ORF Viral Vector | pGMLP004141 | human PAK6 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004141 | human PAK6 Lentivirus particle |
Target information
| Target ID | GM-IP2640 |
| Target Name | PAK6 |
| Gene ID | 56924,214230,296078,701589,100856038,101091201,539224,100071463 |
| Gene Symbol and Synonyms | 4732456M09,PAK5,PAK6 |
| Uniprot Accession | Q9NQU5 |
| Uniprot Entry Name | PAK6_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000137843 |
| Target Classification | Kinase |
The target: PAK6, gene name: PAK6, also named as PAK5. This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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