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Anti-PHACTR1 monoclonal antibody
Pre-made anti-PHACTR1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PHACTR1/PHACTR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2651-Ab-1/ GM-Tg-hg-IP2651-Ab-2 | Anti-Human PHACTR1 monoclonal antibody | Human |
| GM-Tg-rg-IP2651-Ab-1/ GM-Tg-rg-IP2651-Ab-2 | Anti-Rat PHACTR1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2651-Ab-1/ GM-Tg-mg-IP2651-Ab-2 | Anti-Mouse PHACTR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2651-Ab-1/ GM-Tg-cynog-IP2651-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PHACTR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2651-Ab-1/ GM-Tg-felg-IP2651-Ab-2 | Anti-Feline PHACTR1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2651-Ab-1/ GM-Tg-cang-IP2651-Ab-2 | Anti-Canine PHACTR1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2651-Ab-1/ GM-Tg-bovg-IP2651-Ab-2 | Anti-Bovine PHACTR1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2651-Ab-1/ GM-Tg-equg-IP2651-Ab-2 | Anti-Equine PHACTR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2651-Ab-1/ GM-Tg-hg-IP2651-Ab-2; GM-Tg-rg-IP2651-Ab-1/ GM-Tg-rg-IP2651-Ab-2; GM-Tg-mg-IP2651-Ab-1/ GM-Tg-mg-IP2651-Ab-2; GM-Tg-cynog-IP2651-Ab-1/ GM-Tg-cynog-IP2651-Ab-2; GM-Tg-felg-IP2651-Ab-1/ GM-Tg-felg-IP2651-Ab-2; GM-Tg-cang-IP2651-Ab-1/ GM-Tg-cang-IP2651-Ab-2; GM-Tg-bovg-IP2651-Ab-1/ GM-Tg-bovg-IP2651-Ab-2; GM-Tg-equg-IP2651-Ab-1/ GM-Tg-equg-IP2651-Ab-2 |
| Products Name | Anti-PHACTR1 monoclonal antibody |
| Format | mab |
| Target Name | PHACTR1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PHACTR1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2651-Ag-1 | Recombinant multi-species PHAR1/ PHACTR1/ RPEL protein |
| ORF Viral Vector | pGMLPm004967 | mouse Phactr1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004967 | mouse Phactr1 Lentivirus particle |
Target information
| Target ID | GM-IP2651 |
| Target Name | PHACTR1 |
| Gene ID | 221692,218194,306844,700226,478723,101092683,537594,106782323 |
| Gene Symbol and Synonyms | 9630030F18Rik,DEE70,dJ257A7.2,EIEE70,PHACTR1,RPEL,RPEL1 |
| Uniprot Accession | Q9C0D0,P62024 |
| Uniprot Entry Name | PHAR1_HUMAN,PHAR1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112137 |
| Target Classification | N/A |
The target: PHACTR1, gene name: PHACTR1, also named as RPEL, RPEL1, dJ257A7.2. The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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