Anti-PNCK monoclonal antibody

Pre-made anti-PNCK monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PNCK/PNCK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2662-Ab-1/ GM-Tg-hg-IP2662-Ab-2Anti-Human PNCK monoclonal antibodyHuman
GM-Tg-rg-IP2662-Ab-1/ GM-Tg-rg-IP2662-Ab-2Anti-Rat PNCK monoclonal antibodyRat
GM-Tg-mg-IP2662-Ab-1/ GM-Tg-mg-IP2662-Ab-2Anti-Mouse PNCK monoclonal antibodyMouse
GM-Tg-cynog-IP2662-Ab-1/ GM-Tg-cynog-IP2662-Ab-2Anti-Cynomolgus/ Rhesus macaque PNCK monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2662-Ab-1/ GM-Tg-felg-IP2662-Ab-2Anti-Feline PNCK monoclonal antibodyFeline
GM-Tg-cang-IP2662-Ab-1/ GM-Tg-cang-IP2662-Ab-2Anti-Canine PNCK monoclonal antibodyCanine
GM-Tg-bovg-IP2662-Ab-1/ GM-Tg-bovg-IP2662-Ab-2Anti-Bovine PNCK monoclonal antibodyBovine
GM-Tg-equg-IP2662-Ab-1/ GM-Tg-equg-IP2662-Ab-2Anti-Equine PNCK monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2662-Ab-1/ GM-Tg-hg-IP2662-Ab-2; GM-Tg-rg-IP2662-Ab-1/ GM-Tg-rg-IP2662-Ab-2;
GM-Tg-mg-IP2662-Ab-1/ GM-Tg-mg-IP2662-Ab-2; GM-Tg-cynog-IP2662-Ab-1/ GM-Tg-cynog-IP2662-Ab-2;
GM-Tg-felg-IP2662-Ab-1/ GM-Tg-felg-IP2662-Ab-2; GM-Tg-cang-IP2662-Ab-1/ GM-Tg-cang-IP2662-Ab-2;
GM-Tg-bovg-IP2662-Ab-1/ GM-Tg-bovg-IP2662-Ab-2; GM-Tg-equg-IP2662-Ab-1/ GM-Tg-equg-IP2662-Ab-2
Products NameAnti-PNCK monoclonal antibody
Formatmab
Target NamePNCK
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PNCK monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2662-Ag-1Recombinant multi-species KCC1B/ PNCK/ BSTK3 protein


    Target information

    Target IDGM-IP2662
    Target NamePNCK
    Gene ID139728,93843,29660,696413,492241,101087718,614251,111771516
    Gene Symbol and SynonymsBSTK3,CaMK1b,CaMKIbeta2,caMKlb1,CaMKlb2,PNCK,Punc
    Uniprot AccessionQ6P2M8,O70150
    Uniprot Entry NameKCC1B_HUMAN,KCC1B_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000130822
    Target ClassificationKinase

    The target: PNCK, gene name: PNCK, also named as BSTK3, CaMK1b. PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.