Anti-PPP1R9A monoclonal antibody

Pre-made anti-PPP1R9A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PPP1R9A/PPP1R9A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2667-Ab-1/ GM-Tg-hg-IP2667-Ab-2Anti-Human PPP1R9A monoclonal antibodyHuman
GM-Tg-rg-IP2667-Ab-1/ GM-Tg-rg-IP2667-Ab-2Anti-Rat PPP1R9A monoclonal antibodyRat
GM-Tg-mg-IP2667-Ab-1/ GM-Tg-mg-IP2667-Ab-2Anti-Mouse PPP1R9A monoclonal antibodyMouse
GM-Tg-cynog-IP2667-Ab-1/ GM-Tg-cynog-IP2667-Ab-2Anti-Cynomolgus/ Rhesus macaque PPP1R9A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2667-Ab-1/ GM-Tg-felg-IP2667-Ab-2Anti-Feline PPP1R9A monoclonal antibodyFeline
GM-Tg-cang-IP2667-Ab-1/ GM-Tg-cang-IP2667-Ab-2Anti-Canine PPP1R9A monoclonal antibodyCanine
GM-Tg-bovg-IP2667-Ab-1/ GM-Tg-bovg-IP2667-Ab-2Anti-Bovine PPP1R9A monoclonal antibodyBovine
GM-Tg-equg-IP2667-Ab-1/ GM-Tg-equg-IP2667-Ab-2Anti-Equine PPP1R9A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2667-Ab-1/ GM-Tg-hg-IP2667-Ab-2; GM-Tg-rg-IP2667-Ab-1/ GM-Tg-rg-IP2667-Ab-2;
GM-Tg-mg-IP2667-Ab-1/ GM-Tg-mg-IP2667-Ab-2; GM-Tg-cynog-IP2667-Ab-1/ GM-Tg-cynog-IP2667-Ab-2;
GM-Tg-felg-IP2667-Ab-1/ GM-Tg-felg-IP2667-Ab-2; GM-Tg-cang-IP2667-Ab-1/ GM-Tg-cang-IP2667-Ab-2;
GM-Tg-bovg-IP2667-Ab-1/ GM-Tg-bovg-IP2667-Ab-2; GM-Tg-equg-IP2667-Ab-1/ GM-Tg-equg-IP2667-Ab-2
Products NameAnti-PPP1R9A monoclonal antibody
Formatmab
Target NamePPP1R9A
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PPP1R9A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2667-Ag-1Recombinant multi-species NEB1/ PPP1R9A/ NRB1 protein


    Target information

    Target IDGM-IP2667
    Target NamePPP1R9A
    Gene ID55607,243725,84685,699491,482308,101090599,539311,100051837
    Gene Symbol and Synonyms2810430P21Rik,4930518N04Rik,5330407E15,A230094E16Rik,Neb1,Neurabin-I,NRB,NRB1,NRBI,p180,PP1bp175,PPP1R9A
    Uniprot AccessionQ9ULJ8,O35867
    Uniprot Entry NameNEB1_HUMAN,NEB1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158528
    Target ClassificationN/A

    The target: PPP1R9A, gene name: PPP1R9A, also named as NRB1, NRBI, Neurabin-I. This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.