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Anti-RAD52 monoclonal antibody
Pre-made anti-RAD52 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RAD52/RAD52 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2690-Ab-1/ GM-Tg-hg-IP2690-Ab-2 | Anti-Human RAD52 monoclonal antibody | Human |
| GM-Tg-rg-IP2690-Ab-1/ GM-Tg-rg-IP2690-Ab-2 | Anti-Rat RAD52 monoclonal antibody | Rat |
| GM-Tg-mg-IP2690-Ab-1/ GM-Tg-mg-IP2690-Ab-2 | Anti-Mouse RAD52 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2690-Ab-1/ GM-Tg-cynog-IP2690-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RAD52 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2690-Ab-1/ GM-Tg-felg-IP2690-Ab-2 | Anti-Feline RAD52 monoclonal antibody | Feline |
| GM-Tg-cang-IP2690-Ab-1/ GM-Tg-cang-IP2690-Ab-2 | Anti-Canine RAD52 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2690-Ab-1/ GM-Tg-bovg-IP2690-Ab-2 | Anti-Bovine RAD52 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2690-Ab-1/ GM-Tg-equg-IP2690-Ab-2 | Anti-Equine RAD52 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2690-Ab-1/ GM-Tg-hg-IP2690-Ab-2; GM-Tg-rg-IP2690-Ab-1/ GM-Tg-rg-IP2690-Ab-2; GM-Tg-mg-IP2690-Ab-1/ GM-Tg-mg-IP2690-Ab-2; GM-Tg-cynog-IP2690-Ab-1/ GM-Tg-cynog-IP2690-Ab-2; GM-Tg-felg-IP2690-Ab-1/ GM-Tg-felg-IP2690-Ab-2; GM-Tg-cang-IP2690-Ab-1/ GM-Tg-cang-IP2690-Ab-2; GM-Tg-bovg-IP2690-Ab-1/ GM-Tg-bovg-IP2690-Ab-2; GM-Tg-equg-IP2690-Ab-1/ GM-Tg-equg-IP2690-Ab-2 |
| Products Name | Anti-RAD52 monoclonal antibody |
| Format | mab |
| Target Name | RAD52 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RAD52 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2690-Ag-1 | Recombinant multi-species RAD52 protein |
| ORF Viral Vector | vGMLP001723 | human RAD52 Lentivirus particle |
| ORF Viral Vector | pGMLP001723 | human RAD52 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003967 | mouse Rad52 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003967 | mouse Rad52 Lentivirus particle |
Target information
| Target ID | GM-IP2690 |
| Target Name | RAD52 |
| Gene ID | 5893,19365,297561,100426645,477729,101087072,512897,100050254 |
| Gene Symbol and Synonyms | RAD52,Rad52yh |
| Uniprot Accession | P43351 |
| Uniprot Entry Name | RAD52_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000002016 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: RAD52, gene name: RAD52, also named as . The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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