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Anti-RGS7BP monoclonal antibody
Pre-made anti-RGS7BP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RGS7BP/RGS7BP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2701-Ab-1/ GM-Tg-hg-IP2701-Ab-2 | Anti-Human RGS7BP monoclonal antibody | Human |
| GM-Tg-rg-IP2701-Ab-1/ GM-Tg-rg-IP2701-Ab-2 | Anti-Rat RGS7BP monoclonal antibody | Rat |
| GM-Tg-mg-IP2701-Ab-1/ GM-Tg-mg-IP2701-Ab-2 | Anti-Mouse RGS7BP monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2701-Ab-1/ GM-Tg-cynog-IP2701-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RGS7BP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2701-Ab-1/ GM-Tg-felg-IP2701-Ab-2 | Anti-Feline RGS7BP monoclonal antibody | Feline |
| GM-Tg-cang-IP2701-Ab-1/ GM-Tg-cang-IP2701-Ab-2 | Anti-Canine RGS7BP monoclonal antibody | Canine |
| GM-Tg-bovg-IP2701-Ab-1/ GM-Tg-bovg-IP2701-Ab-2 | Anti-Bovine RGS7BP monoclonal antibody | Bovine |
| GM-Tg-equg-IP2701-Ab-1/ GM-Tg-equg-IP2701-Ab-2 | Anti-Equine RGS7BP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2701-Ab-1/ GM-Tg-hg-IP2701-Ab-2; GM-Tg-rg-IP2701-Ab-1/ GM-Tg-rg-IP2701-Ab-2; GM-Tg-mg-IP2701-Ab-1/ GM-Tg-mg-IP2701-Ab-2; GM-Tg-cynog-IP2701-Ab-1/ GM-Tg-cynog-IP2701-Ab-2; GM-Tg-felg-IP2701-Ab-1/ GM-Tg-felg-IP2701-Ab-2; GM-Tg-cang-IP2701-Ab-1/ GM-Tg-cang-IP2701-Ab-2; GM-Tg-bovg-IP2701-Ab-1/ GM-Tg-bovg-IP2701-Ab-2; GM-Tg-equg-IP2701-Ab-1/ GM-Tg-equg-IP2701-Ab-2 |
| Products Name | Anti-RGS7BP monoclonal antibody |
| Format | mab |
| Target Name | RGS7BP |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RGS7BP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2701-Ag-1 | Recombinant multi-species R7BP/ RGS7BP protein |
Target information
| Target ID | GM-IP2701 |
| Target Name | RGS7BP |
| Gene ID | 401190,52882,294715,695221,609560,101080356,613327,100057970 |
| Gene Symbol and Synonyms | A930030I01Rik,D13Bwg1146e,R7BP,RGD1309360,RGS7BP |
| Uniprot Accession | Q6MZT1,Q5FVH8,Q08DH5 |
| Uniprot Entry Name | R7BP_HUMAN,R7BP_RAT,R7BP_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000186479 |
| Target Classification | N/A |
The target: RGS7BP, gene name: RGS7BP, also named as R7BP. This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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