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Anti-RIMS2 monoclonal antibody
Pre-made anti-RIMS2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RIMS2/RIMS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2707-Ab-1/ GM-Tg-hg-IP2707-Ab-2 | Anti-Human RIMS2 monoclonal antibody | Human |
| GM-Tg-rg-IP2707-Ab-1/ GM-Tg-rg-IP2707-Ab-2 | Anti-Rat RIMS2 monoclonal antibody | Rat |
| GM-Tg-mg-IP2707-Ab-1/ GM-Tg-mg-IP2707-Ab-2 | Anti-Mouse RIMS2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2707-Ab-1/ GM-Tg-cynog-IP2707-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RIMS2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2707-Ab-1/ GM-Tg-felg-IP2707-Ab-2 | Anti-Feline RIMS2 monoclonal antibody | Feline |
| GM-Tg-cang-IP2707-Ab-1/ GM-Tg-cang-IP2707-Ab-2 | Anti-Canine RIMS2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2707-Ab-1/ GM-Tg-bovg-IP2707-Ab-2 | Anti-Bovine RIMS2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2707-Ab-1/ GM-Tg-equg-IP2707-Ab-2 | Anti-Equine RIMS2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2707-Ab-1/ GM-Tg-hg-IP2707-Ab-2; GM-Tg-rg-IP2707-Ab-1/ GM-Tg-rg-IP2707-Ab-2; GM-Tg-mg-IP2707-Ab-1/ GM-Tg-mg-IP2707-Ab-2; GM-Tg-cynog-IP2707-Ab-1/ GM-Tg-cynog-IP2707-Ab-2; GM-Tg-felg-IP2707-Ab-1/ GM-Tg-felg-IP2707-Ab-2; GM-Tg-cang-IP2707-Ab-1/ GM-Tg-cang-IP2707-Ab-2; GM-Tg-bovg-IP2707-Ab-1/ GM-Tg-bovg-IP2707-Ab-2; GM-Tg-equg-IP2707-Ab-1/ GM-Tg-equg-IP2707-Ab-2 |
| Products Name | Anti-RIMS2 monoclonal antibody |
| Format | mab |
| Target Name | RIMS2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RIMS2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2707-Ag-1 | Recombinant multi-species RIMS2/ OBOE/ RAB3IP3 protein |
Target information
| Target ID | GM-IP2707 |
| Target Name | RIMS2 |
| Gene ID | 9699,116838,116839,694366,475066,101080764,535674,100062793 |
| Gene Symbol and Synonyms | 2810036I15Rik,CRSDS,mKIAA0751,Nim2,OBOE,Rab3ip2,RAB3IP3,RIM2,Rim2(+40A),Rim2(+44A),Rim2(+4A),RIMS2,Serg2,Syt3-rs |
| Uniprot Accession | Q9UQ26,Q9JIS1 |
| Uniprot Entry Name | RIMS2_HUMAN,RIMS2_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000176406 |
| Target Classification | N/A |
The target: RIMS2, gene name: RIMS2, also named as OBOE, RAB3IP3, RIM2. The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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