Anti-RTL3 monoclonal antibody

Pre-made anti-RTL3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RTL3/RTL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2721-Ab-1/ GM-Tg-hg-IP2721-Ab-2Anti-Human RTL3 monoclonal antibodyHuman
GM-Tg-rg-IP2721-Ab-1/ GM-Tg-rg-IP2721-Ab-2Anti-Rat RTL3 monoclonal antibodyRat
GM-Tg-mg-IP2721-Ab-1/ GM-Tg-mg-IP2721-Ab-2Anti-Mouse RTL3 monoclonal antibodyMouse
GM-Tg-cynog-IP2721-Ab-1/ GM-Tg-cynog-IP2721-Ab-2Anti-Cynomolgus/ Rhesus macaque RTL3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2721-Ab-1/ GM-Tg-felg-IP2721-Ab-2Anti-Feline RTL3 monoclonal antibodyFeline
GM-Tg-cang-IP2721-Ab-1/ GM-Tg-cang-IP2721-Ab-2Anti-Canine RTL3 monoclonal antibodyCanine
GM-Tg-bovg-IP2721-Ab-1/ GM-Tg-bovg-IP2721-Ab-2Anti-Bovine RTL3 monoclonal antibodyBovine
GM-Tg-equg-IP2721-Ab-1/ GM-Tg-equg-IP2721-Ab-2Anti-Equine RTL3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2721-Ab-1/ GM-Tg-hg-IP2721-Ab-2; GM-Tg-rg-IP2721-Ab-1/ GM-Tg-rg-IP2721-Ab-2;
GM-Tg-mg-IP2721-Ab-1/ GM-Tg-mg-IP2721-Ab-2; GM-Tg-cynog-IP2721-Ab-1/ GM-Tg-cynog-IP2721-Ab-2;
GM-Tg-felg-IP2721-Ab-1/ GM-Tg-felg-IP2721-Ab-2; GM-Tg-cang-IP2721-Ab-1/ GM-Tg-cang-IP2721-Ab-2;
GM-Tg-bovg-IP2721-Ab-1/ GM-Tg-bovg-IP2721-Ab-2; GM-Tg-equg-IP2721-Ab-1/ GM-Tg-equg-IP2721-Ab-2
Products NameAnti-RTL3 monoclonal antibody
Formatmab
Target NameRTL3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RTL3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2721-Ag-1Recombinant multi-species RTL3/3-Mar/ Mart3 protein


    Target information

    Target IDGM-IP2721
    Target NameRTL3
    Gene ID203430,213436,317221,706957,100683734,101089173,506964,100072624
    Gene Symbol and SynonymsD430021I08Rik,Gm375,Mar3,Mart3,RGD1564805,RTL3,SIRH9,ZCCHC5,ZHC5
    Uniprot AccessionQ8N8U3
    Uniprot Entry NameRTL3_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179300
    Target ClassificationN/A

    The target: RTL3, gene name: RTL3, also named as Mar3, Mart3, SIRH9, ZCCHC5, ZHC5. This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell. [provided by RefSeq, Nov 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.