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Anti-SCEL monoclonal antibody
Pre-made anti-SCEL monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SCEL/SCEL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2729-Ab-1/ GM-Tg-hg-IP2729-Ab-2 | Anti-Human SCEL monoclonal antibody | Human |
| GM-Tg-rg-IP2729-Ab-1/ GM-Tg-rg-IP2729-Ab-2 | Anti-Rat SCEL monoclonal antibody | Rat |
| GM-Tg-mg-IP2729-Ab-1/ GM-Tg-mg-IP2729-Ab-2 | Anti-Mouse SCEL monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2729-Ab-1/ GM-Tg-cynog-IP2729-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SCEL monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2729-Ab-1/ GM-Tg-felg-IP2729-Ab-2 | Anti-Feline SCEL monoclonal antibody | Feline |
| GM-Tg-cang-IP2729-Ab-1/ GM-Tg-cang-IP2729-Ab-2 | Anti-Canine SCEL monoclonal antibody | Canine |
| GM-Tg-bovg-IP2729-Ab-1/ GM-Tg-bovg-IP2729-Ab-2 | Anti-Bovine SCEL monoclonal antibody | Bovine |
| GM-Tg-equg-IP2729-Ab-1/ GM-Tg-equg-IP2729-Ab-2 | Anti-Equine SCEL monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2729-Ab-1/ GM-Tg-hg-IP2729-Ab-2; GM-Tg-rg-IP2729-Ab-1/ GM-Tg-rg-IP2729-Ab-2; GM-Tg-mg-IP2729-Ab-1/ GM-Tg-mg-IP2729-Ab-2; GM-Tg-cynog-IP2729-Ab-1/ GM-Tg-cynog-IP2729-Ab-2; GM-Tg-felg-IP2729-Ab-1/ GM-Tg-felg-IP2729-Ab-2; GM-Tg-cang-IP2729-Ab-1/ GM-Tg-cang-IP2729-Ab-2; GM-Tg-bovg-IP2729-Ab-1/ GM-Tg-bovg-IP2729-Ab-2; GM-Tg-equg-IP2729-Ab-1/ GM-Tg-equg-IP2729-Ab-2 |
| Products Name | Anti-SCEL monoclonal antibody |
| Format | mab |
| Target Name | SCEL |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SCEL monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2729-Ag-1 | Recombinant multi-species SCEL protein |
Target information
| Target ID | GM-IP2729 |
| Target Name | SCEL |
| Gene ID | 8796,64929,361086,696980,100683601,101089485,784362,100629247 |
| Gene Symbol and Synonyms | 9230114I02Rik,SCEL |
| Uniprot Accession | O95171 |
| Uniprot Entry Name | SCEL_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000136155 |
| Target Classification | N/A |
The target: SCEL, gene name: SCEL, also named as . The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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