Anti-SEC16B monoclonal antibody

Pre-made anti-SEC16B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SEC16B/SEC16B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2731-Ab-1/ GM-Tg-hg-IP2731-Ab-2Anti-Human SEC16B monoclonal antibodyHuman
GM-Tg-rg-IP2731-Ab-1/ GM-Tg-rg-IP2731-Ab-2Anti-Rat SEC16B monoclonal antibodyRat
GM-Tg-mg-IP2731-Ab-1/ GM-Tg-mg-IP2731-Ab-2Anti-Mouse SEC16B monoclonal antibodyMouse
GM-Tg-cynog-IP2731-Ab-1/ GM-Tg-cynog-IP2731-Ab-2Anti-Cynomolgus/ Rhesus macaque SEC16B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2731-Ab-1/ GM-Tg-felg-IP2731-Ab-2Anti-Feline SEC16B monoclonal antibodyFeline
GM-Tg-cang-IP2731-Ab-1/ GM-Tg-cang-IP2731-Ab-2Anti-Canine SEC16B monoclonal antibodyCanine
GM-Tg-bovg-IP2731-Ab-1/ GM-Tg-bovg-IP2731-Ab-2Anti-Bovine SEC16B monoclonal antibodyBovine
GM-Tg-equg-IP2731-Ab-1/ GM-Tg-equg-IP2731-Ab-2Anti-Equine SEC16B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2731-Ab-1/ GM-Tg-hg-IP2731-Ab-2; GM-Tg-rg-IP2731-Ab-1/ GM-Tg-rg-IP2731-Ab-2;
GM-Tg-mg-IP2731-Ab-1/ GM-Tg-mg-IP2731-Ab-2; GM-Tg-cynog-IP2731-Ab-1/ GM-Tg-cynog-IP2731-Ab-2;
GM-Tg-felg-IP2731-Ab-1/ GM-Tg-felg-IP2731-Ab-2; GM-Tg-cang-IP2731-Ab-1/ GM-Tg-cang-IP2731-Ab-2;
GM-Tg-bovg-IP2731-Ab-1/ GM-Tg-bovg-IP2731-Ab-2; GM-Tg-equg-IP2731-Ab-1/ GM-Tg-equg-IP2731-Ab-2
Products NameAnti-SEC16B monoclonal antibody
Formatmab
Target NameSEC16B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SEC16B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2731-Ag-1Recombinant multi-species SC16B/ SEC16B/ LZTR2 protein


    Target information

    Target IDGM-IP2731
    Target NameSEC16B
    Gene ID89866,89867,89868,101099013,404548,100052827
    Gene Symbol and SynonymsLZTR2,PGPR-p117,RGPR,RGPR-p117,SEC16B,SEC16S
    Uniprot AccessionQ96JE7,Q75N33,Q75NY9
    Uniprot Entry NameSC16B_HUMAN,SC16B_RAT,SC16B_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000120341
    Target ClassificationN/A

    The target: SEC16B, gene name: SEC16B, also named as LZTR2, PGPR-p117, RGPR, RGPR-p117, SEC16S. SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.