Anti-SENP5 monoclonal antibody

Pre-made anti-SENP5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SENP5/SENP5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2732-Ab-1/ GM-Tg-hg-IP2732-Ab-2Anti-Human SENP5 monoclonal antibodyHuman
GM-Tg-rg-IP2732-Ab-1/ GM-Tg-rg-IP2732-Ab-2Anti-Rat SENP5 monoclonal antibodyRat
GM-Tg-mg-IP2732-Ab-1/ GM-Tg-mg-IP2732-Ab-2Anti-Mouse SENP5 monoclonal antibodyMouse
GM-Tg-cynog-IP2732-Ab-1/ GM-Tg-cynog-IP2732-Ab-2Anti-Cynomolgus/ Rhesus macaque SENP5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2732-Ab-1/ GM-Tg-felg-IP2732-Ab-2Anti-Feline SENP5 monoclonal antibodyFeline
GM-Tg-cang-IP2732-Ab-1/ GM-Tg-cang-IP2732-Ab-2Anti-Canine SENP5 monoclonal antibodyCanine
GM-Tg-bovg-IP2732-Ab-1/ GM-Tg-bovg-IP2732-Ab-2Anti-Bovine SENP5 monoclonal antibodyBovine
GM-Tg-equg-IP2732-Ab-1/ GM-Tg-equg-IP2732-Ab-2Anti-Equine SENP5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2732-Ab-1/ GM-Tg-hg-IP2732-Ab-2; GM-Tg-rg-IP2732-Ab-1/ GM-Tg-rg-IP2732-Ab-2;
GM-Tg-mg-IP2732-Ab-1/ GM-Tg-mg-IP2732-Ab-2; GM-Tg-cynog-IP2732-Ab-1/ GM-Tg-cynog-IP2732-Ab-2;
GM-Tg-felg-IP2732-Ab-1/ GM-Tg-felg-IP2732-Ab-2; GM-Tg-cang-IP2732-Ab-1/ GM-Tg-cang-IP2732-Ab-2;
GM-Tg-bovg-IP2732-Ab-1/ GM-Tg-bovg-IP2732-Ab-2; GM-Tg-equg-IP2732-Ab-1/ GM-Tg-equg-IP2732-Ab-2
Products NameAnti-SENP5 monoclonal antibody
Formatmab
Target NameSENP5
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SENP5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2732-Ag-1Recombinant multi-species SENP5 protein


    Target information

    Target IDGM-IP2732
    Target NameSENP5
    Gene ID205564,320213,103689978,710223,488033,101088182,100298192,100069684
    Gene Symbol and Synonyms6230429P13Rik,A730063F07Rik,SENP5,SMT3IP3
    Uniprot AccessionQ96HI0
    Uniprot Entry NameSENP5_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000119231
    Target ClassificationN/A

    The target: SENP5, gene name: SENP5, also named as . The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.