Anti-SH3BGR monoclonal antibody

Pre-made anti-SH3BGR monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SH3BGR/SH3BGR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2736-Ab-1/ GM-Tg-hg-IP2736-Ab-2Anti-Human SH3BGR monoclonal antibodyHuman
GM-Tg-rg-IP2736-Ab-1/ GM-Tg-rg-IP2736-Ab-2Anti-Rat SH3BGR monoclonal antibodyRat
GM-Tg-mg-IP2736-Ab-1/ GM-Tg-mg-IP2736-Ab-2Anti-Mouse SH3BGR monoclonal antibodyMouse
GM-Tg-cynog-IP2736-Ab-1/ GM-Tg-cynog-IP2736-Ab-2Anti-Cynomolgus/ Rhesus macaque SH3BGR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2736-Ab-1/ GM-Tg-felg-IP2736-Ab-2Anti-Feline SH3BGR monoclonal antibodyFeline
GM-Tg-cang-IP2736-Ab-1/ GM-Tg-cang-IP2736-Ab-2Anti-Canine SH3BGR monoclonal antibodyCanine
GM-Tg-bovg-IP2736-Ab-1/ GM-Tg-bovg-IP2736-Ab-2Anti-Bovine SH3BGR monoclonal antibodyBovine
GM-Tg-equg-IP2736-Ab-1/ GM-Tg-equg-IP2736-Ab-2Anti-Equine SH3BGR monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2736-Ab-1/ GM-Tg-hg-IP2736-Ab-2; GM-Tg-rg-IP2736-Ab-1/ GM-Tg-rg-IP2736-Ab-2;
GM-Tg-mg-IP2736-Ab-1/ GM-Tg-mg-IP2736-Ab-2; GM-Tg-cynog-IP2736-Ab-1/ GM-Tg-cynog-IP2736-Ab-2;
GM-Tg-felg-IP2736-Ab-1/ GM-Tg-felg-IP2736-Ab-2; GM-Tg-cang-IP2736-Ab-1/ GM-Tg-cang-IP2736-Ab-2;
GM-Tg-bovg-IP2736-Ab-1/ GM-Tg-bovg-IP2736-Ab-2; GM-Tg-equg-IP2736-Ab-1/ GM-Tg-equg-IP2736-Ab-2
Products NameAnti-SH3BGR monoclonal antibody
Formatmab
Target NameSH3BGR
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SH3BGR monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2736-Ag-1Recombinant multi-species SH3BG/ SH3BGR/ 21-GARP protein


    Target information

    Target IDGM-IP2736
    Target NameSH3BGR
    Gene ID6450,50795,722581,617797,100059282
    Gene Symbol and Synonyms21-GARP,5430437A18Rik,SH3BGR
    Uniprot AccessionP55822
    Uniprot Entry NameSH3BG_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000185437
    Target ClassificationN/A

    The target: SH3BGR, gene name: SH3BGR, also named as 21-GARP. Predicted to enable SH3 domain binding activity. Predicted to be involved in protein-containing complex assembly. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.