Anti-SLX4 monoclonal antibody

Pre-made anti-SLX4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SLX4/SLX4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2742-Ab-1/ GM-Tg-hg-IP2742-Ab-2Anti-Human SLX4 monoclonal antibodyHuman
GM-Tg-rg-IP2742-Ab-1/ GM-Tg-rg-IP2742-Ab-2Anti-Rat SLX4 monoclonal antibodyRat
GM-Tg-mg-IP2742-Ab-1/ GM-Tg-mg-IP2742-Ab-2Anti-Mouse SLX4 monoclonal antibodyMouse
GM-Tg-cynog-IP2742-Ab-1/ GM-Tg-cynog-IP2742-Ab-2Anti-Cynomolgus/ Rhesus macaque SLX4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2742-Ab-1/ GM-Tg-felg-IP2742-Ab-2Anti-Feline SLX4 monoclonal antibodyFeline
GM-Tg-cang-IP2742-Ab-1/ GM-Tg-cang-IP2742-Ab-2Anti-Canine SLX4 monoclonal antibodyCanine
GM-Tg-bovg-IP2742-Ab-1/ GM-Tg-bovg-IP2742-Ab-2Anti-Bovine SLX4 monoclonal antibodyBovine
GM-Tg-equg-IP2742-Ab-1/ GM-Tg-equg-IP2742-Ab-2Anti-Equine SLX4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2742-Ab-1/ GM-Tg-hg-IP2742-Ab-2; GM-Tg-rg-IP2742-Ab-1/ GM-Tg-rg-IP2742-Ab-2;
GM-Tg-mg-IP2742-Ab-1/ GM-Tg-mg-IP2742-Ab-2; GM-Tg-cynog-IP2742-Ab-1/ GM-Tg-cynog-IP2742-Ab-2;
GM-Tg-felg-IP2742-Ab-1/ GM-Tg-felg-IP2742-Ab-2; GM-Tg-cang-IP2742-Ab-1/ GM-Tg-cang-IP2742-Ab-2;
GM-Tg-bovg-IP2742-Ab-1/ GM-Tg-bovg-IP2742-Ab-2; GM-Tg-equg-IP2742-Ab-1/ GM-Tg-equg-IP2742-Ab-2
Products NameAnti-SLX4 monoclonal antibody
Formatmab
Target NameSLX4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SLX4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2742-Ag-1Recombinant multi-species SLX4/ BTBD12/ FANCP protein


    Target information

    Target IDGM-IP2742
    Target NameSLX4
    Gene ID84464,52864,302953,705887,479867,101095218,512193,100069533
    Gene Symbol and SynonymsBTBD12,D16Bwg1016e,FANCP,MUS312,RGD1566009,SLX4
    Uniprot AccessionQ8IY92
    Uniprot Entry NameSLX4_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000188827
    Target ClassificationN/A

    The target: SLX4, gene name: SLX4, also named as BTBD12, FANCP, MUS312. This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions and critical for cellular responses to replication fork failure. Mutations in this gene were found in patients with Fanconi anemia. [provided by RefSeq, Sep 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.