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Anti-STARD4 monoclonal antibody
Pre-made anti-STARD4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to STARD4/STARD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2757-Ab-1/ GM-Tg-hg-IP2757-Ab-2 | Anti-Human STARD4 monoclonal antibody | Human |
| GM-Tg-rg-IP2757-Ab-1/ GM-Tg-rg-IP2757-Ab-2 | Anti-Rat STARD4 monoclonal antibody | Rat |
| GM-Tg-mg-IP2757-Ab-1/ GM-Tg-mg-IP2757-Ab-2 | Anti-Mouse STARD4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2757-Ab-1/ GM-Tg-cynog-IP2757-Ab-2 | Anti-Cynomolgus/ Rhesus macaque STARD4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2757-Ab-1/ GM-Tg-felg-IP2757-Ab-2 | Anti-Feline STARD4 monoclonal antibody | Feline |
| GM-Tg-cang-IP2757-Ab-1/ GM-Tg-cang-IP2757-Ab-2 | Anti-Canine STARD4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2757-Ab-1/ GM-Tg-bovg-IP2757-Ab-2 | Anti-Bovine STARD4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2757-Ab-1/ GM-Tg-equg-IP2757-Ab-2 | Anti-Equine STARD4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2757-Ab-1/ GM-Tg-hg-IP2757-Ab-2; GM-Tg-rg-IP2757-Ab-1/ GM-Tg-rg-IP2757-Ab-2; GM-Tg-mg-IP2757-Ab-1/ GM-Tg-mg-IP2757-Ab-2; GM-Tg-cynog-IP2757-Ab-1/ GM-Tg-cynog-IP2757-Ab-2; GM-Tg-felg-IP2757-Ab-1/ GM-Tg-felg-IP2757-Ab-2; GM-Tg-cang-IP2757-Ab-1/ GM-Tg-cang-IP2757-Ab-2; GM-Tg-bovg-IP2757-Ab-1/ GM-Tg-bovg-IP2757-Ab-2; GM-Tg-equg-IP2757-Ab-1/ GM-Tg-equg-IP2757-Ab-2 |
| Products Name | Anti-STARD4 monoclonal antibody |
| Format | mab |
| Target Name | STARD4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-STARD4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2757-Ag-1 | Recombinant multi-species STAR4/ STARD4 protein |
Target information
| Target ID | GM-IP2757 |
| Target Name | STARD4 |
| Gene ID | 134429,170459,291699,706654,479141,101086371,100073191 |
| Gene Symbol and Synonyms | 4632419C16Rik,9030213J02Rik,STARD4 |
| Uniprot Accession | Q96DR4 |
| Uniprot Entry Name | STAR4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000164211 |
| Target Classification | N/A |
The target: STARD4, gene name: STARD4, also named as . Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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