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Anti-STIP1 monoclonal antibody
Pre-made anti-STIP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to STIP1/STIP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2759-Ab-1/ GM-Tg-hg-IP2759-Ab-2 | Anti-Human STIP1 monoclonal antibody | Human |
| GM-Tg-rg-IP2759-Ab-1/ GM-Tg-rg-IP2759-Ab-2 | Anti-Rat STIP1 monoclonal antibody | Rat |
| GM-Tg-mg-IP2759-Ab-1/ GM-Tg-mg-IP2759-Ab-2 | Anti-Mouse STIP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2759-Ab-1/ GM-Tg-cynog-IP2759-Ab-2 | Anti-Cynomolgus/ Rhesus macaque STIP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2759-Ab-1/ GM-Tg-felg-IP2759-Ab-2 | Anti-Feline STIP1 monoclonal antibody | Feline |
| GM-Tg-cang-IP2759-Ab-1/ GM-Tg-cang-IP2759-Ab-2 | Anti-Canine STIP1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2759-Ab-1/ GM-Tg-bovg-IP2759-Ab-2 | Anti-Bovine STIP1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2759-Ab-1/ GM-Tg-equg-IP2759-Ab-2 | Anti-Equine STIP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2759-Ab-1/ GM-Tg-hg-IP2759-Ab-2; GM-Tg-rg-IP2759-Ab-1/ GM-Tg-rg-IP2759-Ab-2; GM-Tg-mg-IP2759-Ab-1/ GM-Tg-mg-IP2759-Ab-2; GM-Tg-cynog-IP2759-Ab-1/ GM-Tg-cynog-IP2759-Ab-2; GM-Tg-felg-IP2759-Ab-1/ GM-Tg-felg-IP2759-Ab-2; GM-Tg-cang-IP2759-Ab-1/ GM-Tg-cang-IP2759-Ab-2; GM-Tg-bovg-IP2759-Ab-1/ GM-Tg-bovg-IP2759-Ab-2; GM-Tg-equg-IP2759-Ab-1/ GM-Tg-equg-IP2759-Ab-2 |
| Products Name | Anti-STIP1 monoclonal antibody |
| Format | mab |
| Target Name | STIP1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-STIP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2759-Ag-1 | Recombinant multi-species STIP1/ HEL-S-94n/ HOP protein |
| ORF Viral Vector | vGMLP003250 | human STIP1 Lentivirus particle |
| ORF Viral Vector | pGMLP003250 | human STIP1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003175 | mouse Stip1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003175 | mouse Stip1 Lentivirus particle |
Target information
| Target ID | GM-IP2759 |
| Target Name | STIP1 |
| Gene ID | 10963,20867,192277,717926,474837,101097762,617109,100055100 |
| Gene Symbol and Synonyms | HEL-S-94n,HOP,IEF-SSP-3521,P60,STI1,STI1L,STIP1 |
| Uniprot Accession | P31948,O35814,Q3ZBZ8 |
| Uniprot Entry Name | STIP1_HUMAN,STIP1_RAT,STIP1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000168439 |
| Target Classification | N/A |
The target: STIP1, gene name: STIP1, also named as HEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L. STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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