Anti-SUPT6H monoclonal antibody

Pre-made anti-SUPT6H monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SUPT6H/SUPT6H products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2761-Ab-1/ GM-Tg-hg-IP2761-Ab-2Anti-Human SUPT6H monoclonal antibodyHuman
GM-Tg-rg-IP2761-Ab-1/ GM-Tg-rg-IP2761-Ab-2Anti-Rat SUPT6H monoclonal antibodyRat
GM-Tg-mg-IP2761-Ab-1/ GM-Tg-mg-IP2761-Ab-2Anti-Mouse SUPT6H monoclonal antibodyMouse
GM-Tg-cynog-IP2761-Ab-1/ GM-Tg-cynog-IP2761-Ab-2Anti-Cynomolgus/ Rhesus macaque SUPT6H monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2761-Ab-1/ GM-Tg-felg-IP2761-Ab-2Anti-Feline SUPT6H monoclonal antibodyFeline
GM-Tg-cang-IP2761-Ab-1/ GM-Tg-cang-IP2761-Ab-2Anti-Canine SUPT6H monoclonal antibodyCanine
GM-Tg-bovg-IP2761-Ab-1/ GM-Tg-bovg-IP2761-Ab-2Anti-Bovine SUPT6H monoclonal antibodyBovine
GM-Tg-equg-IP2761-Ab-1/ GM-Tg-equg-IP2761-Ab-2Anti-Equine SUPT6H monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2761-Ab-1/ GM-Tg-hg-IP2761-Ab-2; GM-Tg-rg-IP2761-Ab-1/ GM-Tg-rg-IP2761-Ab-2;
GM-Tg-mg-IP2761-Ab-1/ GM-Tg-mg-IP2761-Ab-2; GM-Tg-cynog-IP2761-Ab-1/ GM-Tg-cynog-IP2761-Ab-2;
GM-Tg-felg-IP2761-Ab-1/ GM-Tg-felg-IP2761-Ab-2; GM-Tg-cang-IP2761-Ab-1/ GM-Tg-cang-IP2761-Ab-2;
GM-Tg-bovg-IP2761-Ab-1/ GM-Tg-bovg-IP2761-Ab-2; GM-Tg-equg-IP2761-Ab-1/ GM-Tg-equg-IP2761-Ab-2
Products NameAnti-SUPT6H monoclonal antibody
Formatmab
Target NameSUPT6H
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SUPT6H monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2761-Ag-1Recombinant multi-species SPT6H/ SUPT6H/ SPT6 protein


    Target information

    Target IDGM-IP2761
    Target NameSUPT6H
    Gene ID6830,20926,303281,716230,480627,101097850,538671,100059341
    Gene Symbol and Synonyms5131400N11Rik,emb-5,mKIAA0162,SPT6,SPT6H,Supt6,SUPT6H
    Uniprot AccessionQ7KZ85
    Uniprot Entry NameSPT6H_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000109111
    Target ClassificationN/A

    The target: SUPT6H, gene name: SUPT6H, also named as SPT6, SPT6H, emb-5. Enables histone binding activity. Involved in negative regulation of histone H3-K27 methylation and positive regulation of transcription elongation from RNA polymerase II promoter. Predicted to be located in nucleoplasm. Predicted to be part of transcription elongation factor complex. Predicted to be active in transcriptionally active chromatin. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.